Results 101 to 110 of about 4,864,620 (366)

Optimum Choice of the Front Suspension of an Automobile

Журнал інженерних наук, 2019
The paper details the optimum choice of the front suspension of an automobile. The influence of suspension on the steering geometry is studied by considering the various combinations of joints at the four-bar mechanism of the front suspension.
Belkhode P. N.
doaj   +1 more source

Geometric Description of Schr\"{o}dinger Equation in Finsler and Funk Geometry

, 2019
For a system of $n$ non-relativistic spinless bosons, we show by using a set of suitable matching conditions that the quantum equations in the pilot-wave limit can be translated into a geometric language for a Finslerian manifold.
Bashir, Asma, Koch, Benjamin, Wasay, Muhammad Abdul   +2 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Bis(dicyanamido-κN1)bis[2-(2-hydroxyethyl)pyridine-κ2N,O]nickel(II)

Acta Crystallographica Section E, 2009
In the title complex, [Ni{N(CN)2}2(C7H9NO)2], the NiII ion (site symmetry overline{1}) adopts a distorted trans-NiO2N4 octahedral geometry. In the crystal, intermolecular O—H...N hydrogen bonds link the molecules, forming a chain along the c ...
Da-Cheng Li, Ling-Qian Kong, Xiu-Ping Ju
doaj   +1 more source

Synthetic 3D Spin-Orbit Coupling

, 2012
We describe a method for creating a three-dimensional analogue to Rashba spin-orbit coupling in systems of ultracold atoms. This laser induced coupling uses Raman transitions to link four internal atomic states with a tetrahedral geometry, and gives rise
Brandon M. Anderson, Gediminas Juzeliūnas, I. B. Spielman, L. Landau, Victor M. Galitski   +4 more
core   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

trans-Tris(4-bromophenyl)dichloridoantimony(V)

Acta Crystallographica Section E, 2012
The SbV atom in the title compound, [SbCl2(C6H4Br)3], has an almost regular trigonal–bipyramidal geometry with the equatorial plane made up of three C atoms of the bromophenyl groups and the axial positions occupied by two Cl− ions in
Yanling Qiao, Jin Jiang, Jichun Cui
doaj   +1 more source

Generalized $1$-harmonic Equation and The Inverse Mean Curvature Flow

, 2010
We introduce and study generalized $1$-harmonic equations (1.1). Using some ideas and techniques in studying $1$-harmonic functions from [W1] (2007), and in studying nonhomogeneous $1$-harmonic functions on a cocompact set from [W2, (9.1)] (2008), we ...
Ai-Nung Wang, Bombieri, Bray, Calabi, Cheeger, Chen, Demengel, Evans, Federer, Huisken, Kawohl, Kotschwar, Lin, Moser, Shihshu Walter Wei, Wang, Wei, Wei, Wei, Yau, Yng-Ing Lee   +20 more
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source