Results 111 to 120 of about 3,430,428 (283)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Fuzzy and neutrosophic modeling for link prediction in social networks

, 2019
Some new similarity measures for link prediction based on fuzzy and neutrosophic environments are proposed. It aims to determine possible association between two objects in a social network represented by a graph including nodes and edges.
Ngan, Tran Thi, Chuan, Pham Minh, Tuan, Tran Manh, Ali, Mumtaz, Mittal, Mamta, Son, Le Hoang, Ngan T.T., Tuan T.M., Mittal M., Son L.H., Chuan P.M., Ali M.   +11 more
core   +1 more source

Link Prediction for Indonesian Legislative Candidate

, 2020
<p>Link Prediction for Indonesian Legislative Candidate</p ...
Ghiffari Assamar Qandi, Nur Aini Rakhmawati   +1 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Link Prediction: Theory, Methods and Applications

reservedLa link prediction è un compito fondamentale nell'analisi delle reti che consiste nello stimare la probabilità che un collegamento futuro si formi tra due nodi non ancora connessi, basandosi sulla struttura preesistente della rete e, in alcuni ...
KE, ENOC
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Link prediction in multi-relational collaboration networks

, 2013
Traditional link prediction techniques primarily focus on the effect of potential linkages on the local network neighborhood or the paths between nodes. In this paper, we study the problem of link prediction in networks where instances can simultaneously
Gita Sukthankar, Sukthankar, Gita, Xi Wang, Wang, Xi   +3 more
core   +1 more source

A Review of Link Prediction Algorithms in Dynamic Networks

Mathematics
Dynamic network link prediction refers to the prediction of possible future links or the identification of missing links on the basis of historical information of dynamic networks.
Mengdi Sun, Minghu Tang
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source