Results 91 to 100 of about 173,497 (273)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

System Design and Reliability Improvement of Wireless Sensor Network in Plant Factory Scenario

open access: yesAgronomy
Creating a suitable growing environment is necessary to ensure good plant growth in a plant factory, which requires wireless sensor networks (WSNs) to monitor the environment in real time.
Wenhao Luo   +6 more
doaj   +1 more source

802.11 Link Quality and its Prediction - An Experimental Study

open access: yes, 2008
. Reliable link quality prediction is an imperative for the efficient operation of mobile ad-hoc wireless networks (MANETs). In this paper it is shown that popular link quality prediction algorithms for 802.11 MANETs perform much more poorly when applied
Andrew Butterly   +4 more
core  

Link pattern prediction with tensor decomposition in multi-relational networks

open access: yes, 2011
International audienceWe address the problem of link prediction in collections of objects connected by multiple relation types, where each type may play a distinct role.
Sheng Gao   +5 more
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Temporal link prediction using graph pattern matching [PDF]

open access: yes, 2015
Many real-world systems are composed of individual components which are inter-linked in some way. To understand and predict the behavior of such a system, we can model it as a network where components correspond to nodes and connections are links between
Rümmele, Nataliia
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Genetic Machine Learning Approach for Link Quality Prediction in Mobile Wireless Sensor Networks

open access: yes, 2013
Establishing adequate RF (Radio Frequency) connectivity is the basic requirement for the proper operation of any wireless network. In a mobile wireless network it is a challenge for applications and protocols to deal with connectivity problems, as links ...
Jörg Kaiser   +8 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Leveraging zero tail in neighbourhood for link prediction

open access: yes, 2015
For link prediction, Common Neighbours (CN) ranking measures allow to discover quality links between nodes in a social network, assessing the likelihood of a new link based on the neighbours frontier of the already existing nodes.
Li, Yuanxi   +9 more
core   +1 more source

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