Results 61 to 70 of about 168,484 (241)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Transmission Error Prediction of RV Reducer based on SSA-BP

open access: yesJixie chuandong, 2022
There are many factors affecting the assembly quality of RV (Rotate Vector) reducer, and the assembly quality is unstable. In response to this situation, an optimized BP neural network quality prediction model based on the Sparrow Search Algorithm (SSA ...
Houzhen Sun, Hongbing Yuan, Bin Yu
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Link Quality Prediction for WSNs Based on Dynamic Bayesian Networks

open access: yes工程科学与技术, 2017
:In wireless sensor networks,the link quality prediction is a basic issue in guarantying reliable data transmission and upper network protocol performance.In this paper,a link quality prediction mechanism based on dynamic Bayesian networks (DBN) was ...
SHU Jian   +3 more
doaj  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

A novel SCNN-LSTM model for predicting the SNR confidence interval in wearable wireless sensor network

open access: yesIntelligent Systems with Applications
Accurate real-time prediction of link quality is crucial for enhancing the reliable responsiveness of wearable devices within Wireless Wearable Sensor Networks (WWSNs).
Minghu Zha   +4 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Wireless Sensor Network Modeling and Deployment Challenges in Oil and Gas Refinery Plants

open access: yesInternational Journal of Distributed Sensor Networks, 2013
Wireless sensor networks for critical industrial applications are becoming a remarkable technological paradigm. Large-scale adoption of the wireless connectivity in the field of industrial monitoring and process control is mandatorily paired with the ...
Stefano Savazzi   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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