Results 101 to 110 of about 22,826,976 (294)

Dissecting fruit weight and quality traits in Australian passion fruit through genetic linkage mapping and QTL analysis

Frontiers in Plant Science
IntroductionPassion fruit (Passiflora edulis) is a commercially significant horticultural crop in tropical and subtropical regions. However, the development of high-yielding cultivars with superior fruit quality is currently hindered by limited ...
Xinhang Sun, Peter Bundock, Vivi Arief, Bruce Topp, Mobashwer Alam   +4 more
doaj   +1 more source

Genetic Mapping of Quantitative Trait Loci for Yield-Affecting Traits in a Barley Doubled Haploid Population Derived from Clipper × Sahara 3771

Frontiers in Plant Science, 2017
Many traits play essential roles in determining crop yield. Wide variation for morphological traits exists in Hordeum vulgare L., but the genetic basis of this morphological variation is largely unknown.
Fatemeh Vafadar Shamasbi, Seyed Hossein Jamali, Behzad Sadeghzadeh, Babak Abdollahi Mandoulakani   +3 more
doaj   +1 more source

The analysis of linkages in demographic theory [PDF]

Demography, 1984
Abstract Many seemingly different questions that arise in the analysis of population change can be phrased as the same technical question: How, within a given demographic model, would variable y change if the age- or time-specific function f were to change arbitrarily in shape and intensity?
openaire   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Linkage and association of phospholipid transfer protein activity to LASS4

Journal of Lipid Research, 2011
Phospholipid transfer protein activity (PLTPa) is associated with insulin levels and has been implicated in atherosclerotic disease in both mice and humans.
Elisabeth A. Rosenthal, James Ronald, Joseph Rothstein, Ramakrishnan Rajagopalan, Jane Ranchalis, G. Wolfbauer, John J. Albers, John D. Brunzell, Arno G. Motulsky, Mark J. Rieder, Deborah A. Nickerson, Ellen M. Wijsman, Gail P. Jarvik   +12 more
doaj   +1 more source

Mapping genes through the use of linkage disequilibrium generated by genetic drift: 'Drift mapping' in small populations with no demographic expansion [PDF]

, 1998
Linkage disequilibrium has been a powerful tool in identifying rare disease alleles in human populations. To date, most research has been directed to isolated populations which have undergone a bottleneck followed by rapid exponential expansion.
Zöllner, Sebastian, Laan, Maris, Terwilliger, J., Zöllner, S., Pääbo, S. ; https://orcid.org/, Pääbo, Svante, Laan, M., Terwilliger, Joseph D., Terwilliger, J. D., Maris Laan, Sebastian Zöllner, Joseph D. Terwilliger, Svante Pääbo   +12 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Combinatorial Conflicting Homozygosity (CCH) analysis enables the rapid identification of shared genomic regions in the presence of multiple phenocopies. [PDF]

, 2015
The ability to identify regions of the genome inherited with a dominant trait in one or more families has become increasingly valuable with the wide availability of high throughput sequencing technology.
Neild, GH, Connor, TM, Levine, AP, Maxwell, PH, Gale, DP, Oygar, DD, Segal, AW   +6 more
core   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Spinocerebellar Ataxia

Pediatric Neurology Briefs, 1988
The onset below 15 years of age of autosomal dominant spinocerebellar ataxia (SCA) in 6 of 41 affected patients is reported from the Dept of Pediatrics, Baylor College of Medicine, Houston, TX.
J Gordon Millichap
doaj   +1 more source