Results 251 to 260 of about 537,873 (344)

Significance of linkage disequilibrium and epistasis on genetic variances in noninbred and inbred populations. [PDF]

BMC Genomics, 2022
Viana JMS, Garcia AAF.
europepmc   +1 more source

Linkage disequilibrium in inbred North African families allows fine genetic and physical mapping of triple A syndrome [PDF]

, 2000
S. Hadj‐Rabia, Rémi Salomon, Anna Pelet, Clothilde Penet, Annick Rotschild, Marc‐Henri De Laet, B Chaouachi, R. Hannachi, Fawzi Bakiri, Raja Brauner, Jean‐Louis Chaussain, Arnold Münnich, Stanislas Lyonnet   +12 more
openalex   +1 more source

‘Highly‐Informative’ Genetic Markers Can Bias Conclusions: Examples and General Solutions

Molecular Ecology Resources, EarlyView.
ABSTRACT High‐grading bias is the overestimation power in a subset of loci caused by model overfitting. Using both empirical and simulated datasets, we show that high‐grading bias can cause severe overestimation of population structure, and thus mislead investigators, whenever highly informative or high‐FST markers are chosen (i.e., ascertained) and ...
Andy Lee, William Hemstrom, Natalie Molea, Gordon Luikart, Mark R. Christie   +4 more
wiley   +1 more source

How to handle high subgenome sequence similarity in allopolyploid Fragaria x ananassa: linkage disequilibrium based variant filtering. [PDF]

BMC Genomics
Koorevaar T, Willemsen JH, Hildebrand D, Visser RGF, Arens P, Maliepaard C.   +5 more
europepmc   +1 more source

Properties of 2-locus genealogies and linkage disequilibrium in temporally structured samples. [PDF]

Genetics, 2022
Biddanda A, Steinrücken M, Novembre J.
europepmc   +1 more source

Evaluating linkage and linkage disequilibrium: use of excess sharing and transmission disequilibrium methods in affected sib pairs [PDF]

, 2000
Jacqueline Wicks, Susan R. Wilson
openalex   +1 more source

Comparative Analyses of Four Reference Genomes Reveal Exceptional Diversity and Weak Linked Selection in the Yellow Monkeyflower (Mimulus guttatus) Complex

Molecular Ecology Resources, EarlyView.
ABSTRACT Yellow monkeyflowers (Mimulus guttatus complex, Phrymaceae) are a powerful system for studying ecological adaptation, reproductive variation, and genome evolution. To initiate pan‐genomics in this group, we present four chromosome‐scale assemblies and annotations of accessions spanning a broad evolutionary spectrum: two from a single M ...
John T. Lovell, Rachel Walstead, Amelia Lawrence, Evan Stark‐Dykema, Matthew C. Farnitano, Avril Harder, Tomáš Brůna, Kerrie Barry, David Goodstein, Jerry Jenkins, Anna Lipzen, LoriBeth Boston, Jenell Webber, Mansi Chovatia, Joanne Eichenberger, Jayson Talag, Jane Grimwood, Jeremy Schmutz, John K. Kelly, Andrea L. Sweigart, Lila Fishman, John H. Willis   +21 more
wiley   +1 more source

Genomic exploration of Iranian almond (Prunus dulcis) germplasm: decoding diversity, population structure, and linkage disequilibrium through genotyping-by-sequencing analysis. [PDF]

BMC Genomics
Khojand S, Zeinalabedini M, Azizinezhad R, Imani A, Ghaffari MR.   +4 more
europepmc   +1 more source

Evidence of epistasis in regions of long-range linkage disequilibrium across five complex diseases in the UK Biobank and eMERGE datasets. [PDF]

Am J Hum Genet, 2023
Singhal P, Veturi Y, Dudek SM, Lucas A, Frase A, van Steen K, Schrodi SJ, Fasel D, Weng C, Pendergrass R, Schaid DJ, Kullo IJ, Dikilitas O, Sleiman PMA, Hakonarson H, Moore JH, Williams SM, Ritchie MD, Verma SS.   +18 more
europepmc   +1 more source

Linkage Mapping vs. Association: A Comparison of Two RADseq‐Based Approaches to Identify Markers for Homomorphic Sex Chromosomes in Large Genomes

Molecular Ecology Resources, EarlyView.
ABSTRACT Reliable tools for the identification of genetic sex are invaluable in many fields of biology, but their design requires knowledge of sex‐linked sequences, which is lacking in many taxa. Restriction‐site‐associated DNA sequencing (RADseq) is widely used to identify sex‐linked markers, but multiple distinct strategies are employed, and it is ...
James France, Wiesław Babik, Katarzyna Dudek, Marzena Marszałek, Ben Wielstra   +4 more
wiley   +1 more source