Results 251 to 260 of about 186,640 (297)

Mapping genes for quantitative traits using linkage disequilibrium

Genetics Selection Evolution, 1991
Goddard ME
doaj   +1 more source

An Isochore Transition in the NF1 Gene Region Coincides with a Switch in the Extent of Linkage Disequilibrium

, 2000
Ingrid Eisenbarth, G Vogel, W. Krone, Walther Vogel, Günter Assum   +4 more
openalex   +1 more source

Modifier locus for mitochondrial DNA disease: Linkage and linkage disequilibrium mapping of a nuclear modifier gene for maternally inherited deafness [PDF]

, 2001
Yelena Bykhovskaya, Huiying Yang, Kent D. Taylor, Tieu Hang, Richard Y M Tun, Xavier Estivill, Rosaria A.M.S. Casano, Kari Majamaa, Mordechai Shohat, Nathan Fischel‐Ghodsian   +9 more
openalex   +1 more source

Real‐world clinical experience with NGS‐based chimerism analyses in haematopoietic stem cell transplant patients

British Journal of Haematology, EarlyView.
This study demonstrates the clinical utility of a next‐generation sequencing (NGS)‐based chimerism assay (CASAL) in haematopoietic stem cell transplantation (HSCT). Compared to conventional short tandem repeat (STR) methods, CASAL showed significantly higher marker informativeness, detecting mixed chimerism (MC) below 5% recipient DNA with a median of ...
Jin Ju Kim, Soon Sung Kwon, Yu Jeong Choi, Yehyun Kang, Yu Jin Park, Saeam Shin, Seung‐Tae Lee, Jong Rak Choi   +7 more
wiley   +1 more source

A Genomewide Linkage-Disequilibrium Scan Localizes the Saguenay–Lac-Saint-Jean Cytochrome Oxidase Deficiency to 2p16 [PDF]

, 2001
Nana Lee, Mark J. Daly, Terrye Delmonte, Eric S. Lander, Fenghao Xu, Thomas J. Hudson, Grant A. Mitchell, Charles Morin, Brian H. Robinson, John D. Rioux   +9 more
openalex   +1 more source

The DCIDE framework: systematic investigation of evolutionary hypotheses, exemplified with autism

Biological Reviews, EarlyView.
ABSTRACT Evolutionary explanations of mental disorders are a longstanding aim of evolutionary psychiatry, but have suffered from complexities including within‐disorder heterogeneity and environmental effects of contemporary societies obscuring possible ancestral functions.
Adam D. Hunt, Adrian V. Jaeggi
wiley   +1 more source

Genetic Association of Primary Angle‐Closure Glaucoma and Disease Progression

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To investigate single‐nucleotide polymorphisms (SNPs) reported in the largest up‐to‐date systematic review and meta‐analysis on primary angle‐closure disease (PACD), on their associations with primary angle‐closure glaucoma (PACG) and disease progression.
Yu Jing Liang, Anni Ling, Poemen P. Chan, Jason C. Yam, Chi Pui Pang, Clement C. Tham, Li Jia Chen   +6 more
wiley   +1 more source

Military‐Connected Adolescents' Coping Strategies and Psychological Well‐Being: The Moderating Role of Family Functioning

Child &Family Social Work, EarlyView.
ABSTRACT Military‐connected adolescents face unique challenges associated with military life, and some coping strategies are more beneficial to their well‐being than others. It is important to understand their use of various coping strategies in connection with their psychological well‐being and if there are family circumstances in which these coping ...
Meredith L. Farnsworth, Catherine W. O'Neal   +1 more
wiley   +1 more source

Targeting FABP4 to Inhibit AGEs‐RAGE/NF‐κB Signalling Effectively Ameliorates Nucleus Pulposus Dysfunction and Angiogenesis in Obesity‐Related Intervertebral Disc Degeneration

Cell Proliferation, EarlyView.
Obesity promotes the progression of intervertebral disc degeneration (IVDD) through the mTORC1/FABP4 axis. Targeting FABP4 effectively ameliorates nucleus pulposus dysfunction and angiogenesis in obesity‐related IVDD. ABSTRACT Intervertebral disc degeneration (IVDD) is a primary contributor to low back pain, posing significant social and economic ...
Lin Han, Fudong Li, Huiqiao Wu, Weiheng Wang, Peiwen Chen, Weicheng Xia, Yang Liu, Kaiqiang Sun, Wenbo Lin   +8 more
wiley   +1 more source

GAUSS: a summary-statistics-based R package for accurate estimation of linkage disequilibrium for variants, Gaussian imputation, and TWAS analysis of cosmopolitan cohorts. [PDF]

Bioinformatics
Lee D, Bacanu SA.
europepmc   +1 more source