Results 231 to 240 of about 193,370 (286)

TNF‑α Gene Polymorphisms as Determinants of Alloantibody Emergence in Hemophilia: A Systematic Review and Meta‐Analysis

Haemophilia, EarlyView.
ABSTRACT Introduction Inhibitor development remains one of the most serious complications of replacement therapy in patients with hemophilia. Tumour necrosis factor‐alpha (TNF‐α) is a key pro‐inflammatory cytokine, and its genetic variants have been implicated in immune‐related conditions.
Alessandra Faustino da Conceição Bezerra, Natã Abner Andrade Carito de Sousa, Suely Meireles Rezende, Renan Pedra de Souza   +3 more
wiley   +1 more source

The Impact of Patterns in Linkage Disequilibrium and Sequencing Quality on the Imprint of Balancing Selection. [PDF]

Genome Biol Evol
Hayeck TJ, Li Y, Mosbruger TL, Bradfield JP, Gleason AG, Damianos G, Shaw GT, Duke JL, Conlin LK, Turner TN, Fernández-Viña MA, Sarmady M, Monos DS.   +12 more
europepmc   +1 more source

Pairwise Imitation and Tournament Graphs

International Economic Review, EarlyView.
ABSTRACT This paper investigates strategic dynamics under the behavioral rule of pairwise interact and imitate (PII), which requires minimal information and emphasizes outperforming opponents in pairwise interactions. We characterize PII using weak tournament graphs and, for a broad class of dynamics, establish a one‐shot stability result for ...
Sung‐Ha Hwang, Philip R. Neary, Jonathan Newton, Ryoji Sawa   +3 more
wiley   +1 more source

Genetic Determinants of Peanut‐Specific IgG4 Levels in the Context of Sustained Oral Peanut Exposure in the LEAP Study

Immunology, EarlyView.
A cumulative genetic score based on IgG4‐associated variants explains a substantial proportion of variance in psIgG4 levels during sustained peanut consumption, highlighting strong gene‐by‐environment interactions. Our findings suggest that early, sustained peanut consumption, in combination with genetic factors, promotes a protective immune response ...
Kanika Kanchan, Karen Cerosaletti, James A. Perry, George DuToit, Monali Manohar, Hua Ling, Justin E. Paschall, Srinath Sanda, R. Sharon Chinthrajah, Gerald T. Nepom, Kari C. Nadeau, Stacie M. Jones, Gideon Lack, Ingo Ruczinski, Rasika A. Mathias   +14 more
wiley   +1 more source

Linkage Disequilibrium (LD) [PDF]

, 2019
openaire   +1 more source

Variants in Genes Encoding Innate Lymphoid Cells Type 2 Surface Markers Affecting Asthma and Atopy Pathologies

Clinical &Experimental Allergy, EarlyView.
Raphael Chagas Silva, Gabriela Pimentel Pinheiro, Hátilla dos Santos Silva, Talita dos Santos de Jesus, Carolina Melo Orrico‐Ferreira, Jamille Souza Fernandes Chiarelotto, Cinthia Vila Nova Santana, Carina da Silva Pinheiro, Ricardo Riccio Oliveira, Álvaro Augusto Cruz, Kathleen C. Barnes, Neuza Maria A. Neves, Ryan dos Santos Costa, Camila Alexandrina Figueiredo   +13 more
wiley   +1 more source

Moral Distress Among Family Caregivers: A Concept Analysis

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To examine and define the concept of moral distress among family caregivers by identifying its key attributes, antecedents and consequences. Design Concept analysis. Methods This study was guided by Walker and Avant's concept analysis framework.
Tharaa Ananzeh, Caroline F. Morrison, Elaine L. Miller, Natalie Kreitzer, Tamilyn Bakas   +4 more
wiley   +1 more source

Unravelling the Genetic Mechanisms of Litter Traits in a Maternal Line of Pigs

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Reproductive traits related to litter size are the main indicators of reproductive efficiency in pig production and are continuously evaluated for the selection of maternal lines. Several environmental and genetic factors are involved with the development of these traits.
Guilherme Oselame, Suelen Fernandes Padilha, Maurício Egídio Cantão, Jane de Oliveira Peixoto, Aline Zampar, Adriana Mércia Guaratini Ibelli, Luis Orlando Duitama Carreño, Jader Silva Lopes, Pedro Henrique Ferreira Freitas, Marcelo Silva Freitas, Mônica Corrêa Ledur   +10 more
wiley   +1 more source

Genetic Parameters and Genome‐Wide Association Studies for Fertility and Reproduction Traits in U.S. Katahdin Sheep Based on the Single‐Step GBLUP Methodology

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Sheep production contributes to a secure and diverse food and fibre supply in the United States, with growing ethnic diversity strengthening demand. Katahdin is a composite hair‐type sheep breed developed in the United States that has become the most popular breed in many regions of the country and the first one to have genomic selection ...
Alejandra Toro Ospina, Ronald M. Lewis, Bradley A. Freking, Joan M. Burke, Thomas W. Murphy, Carrie S. Wilson, Luiz F. Brito   +6 more
wiley   +1 more source

Better Multi‐Breed Genomic Predictions for Tropical Bull Fertility Using a Breed‐Adjusted Genomic Relationship Matrix

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT The pressing requirement for agricultural systems to adopt climate change adaptation strategies specifically designed for tropical environments underscores the significance of implementing sustainable bull breeding practices in beef cattle operations.
Antonio Reverter, Pâmela A. Alexandre, Marina R. S. Fortes, Laercio R. Porto‐Neto   +3 more
wiley   +1 more source