Results 251 to 260 of about 128,160 (292)

GAUSS: a summary-statistics-based R package for accurate estimation of linkage disequilibrium for variants, Gaussian imputation, and TWAS analysis of cosmopolitan cohorts. [PDF]

Bioinformatics
Lee D, Bacanu SA.
europepmc   +1 more source

Functional Genetic Variation in Ubiquitin D Promoter Influences Susceptibility to Atopic Dermatitis

Clinical &Experimental Allergy, EarlyView.
Yi Ying Eliza Lim, Yang Yie Sio, Terence Yin Weng Lam, Yee‐How Say, Kavita Reginald, Fook Tim Chew   +5 more
wiley   +1 more source

Linkage Disequilibrium

, 2014
Linkage disequilibrium.
Madalene A. Earp, Ellen L. Goode
openaire   +2 more sources

Linkage disequilibrium between rare mutations [PDF]

Genetics, 2022
Benjamin H Good, S Gravel, Good Benjamin H   +2 more
exaly   +2 more sources

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On the Formula for Admixture Linkage Disequilibrium

Human Heredity, 2005
Admixture linkage disequilibrium (ALD), a phenomenon created by gene flow between genetically distinct populations, has for some time been used as a tool in gene mapping. It is therefore important to analyze the pattern of ALD over generations. In this study we explore two models of admixture: the gradual admixture (GA) model, in which admixture occurs
Guo, J, Fung, WK, Guo, W, Shi, N
openaire   +4 more sources

Linkage Disequilibrium and the Infinitesimal Limit

Theoretical Population Biology, 1997
Under the classical Fisher-Bulmer infinitesimal model of quantitative genetics, the within-family distribution for an additive trait with no environmental component is Gaussian with mean at the mid-parent value and a variance which is the same for all families.
openaire   +2 more sources

Inferences about Linkage Disequilibrium

Biometrics, 1979
Existing theory for inferences about linkage disequilibrium is restricted to a measure defined on gametic frequencies. Unless gametic frequencies are directly observable, they are inferred from genotypic frequencies under the assumption of random union of gametes.
openaire   +3 more sources

Linkage disequilibrium in finite populations

Theoretical and Applied Genetics, 1968
A theoretical investigation has been made of the influence of population size (N) and recombination fraction (c) on linkage disequilibrium (D) between a pair of loci. Two situations were studied: (i) where both loci had no effect on fitness and (ii) where they showed heterozygote superiority, but no epistacy.If the populations are initially in linkage ...
W G, Hill, A, Robertson
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Linkage Disequilibrium or Epistasis?

Tissue Antigens, 1975
M, Segall, F H, Bach
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Linkage Disequilibrium and Association Mapping

Annual Review of Genomics and Human Genetics, 2008
Linkage disequilibrium refers to the association between alleles at different loci. The standard definition applies to two alleles in the same gamete, and it can be regarded as the covariance of indicator variables for the states of those two alleles. The corresponding correlation coefficient ρ is the parameter that arises naturally in discussions of ...
openaire   +2 more sources