Results 261 to 270 of about 537,873 (344)

Genetic insights into the effect of trace elements on cardiovascular diseases: multi-omics Mendelian randomization combined with linkage disequilibrium score regression analysis. [PDF]

Front Immunol
Chen B, Wang C, Li W.
europepmc   +1 more source

Pre‐Vaccination Immunotypes and Immune Entropy Are Indicators of Multiple Vaccine Responsiveness

Aging Cell, EarlyView.
Pre‐vaccination immune profiles and a novel biomarker, immune entropy, are associated with responsiveness to influenza, pneumococcal, and SARS‐CoV‐2 vaccines, independent of age, sex, and CMV serostatus, and also correlate with inflammaging‐related serum proteins, supporting their potential as indicators of immunosenescence validated across diverse ...
Alper Cevirgel, Marieke van der Heiden, Sudarshan A. Shetty, Markus Viljanen, Martijn Vos, Elske Bijvank, Yannick van Sleen, Celine Imhof, Joeri A. J. Rolwes, Leonard Daniël Samson, Lisa Beckers, Nynke Rots, Josine van Beek, Anne‐Marie Buisman, Debbie van Baarle   +14 more
wiley   +1 more source

Long-range linkage disequilibrium events on the genome of dromedary camels as a signal of epistatic and directional positive selection. [PDF]

Heliyon
Bahbahani H.
europepmc   +1 more source

Short tandem repeat (STR) haplotypes in HLA: an integrated 50-kb STR/linkage disequilibrium/gene map between the RING3 and HLA-B genes and identification of STR haplotype diversification in the class III region [PDF]

, 2001
Igor Vořechovský, Jana Královičová, MichaelD Laycock, A D Webster, Steven G. E. Marsh, J. Alejandro Madrigal, Lennart Hammarström   +6 more
openalex   +1 more source

Linkage disequilibrium — understanding the evolutionary past and mapping the medical future

Nature reviews genetics, 2008
M. Slatkin
semanticscholar   +1 more source

Senescent Microglia Mediate Neuroinflammation‐Induced Cognitive Dysfunction by Selective Elimination of Excitatory Synapses in the Hippocampal CA1

Aging Cell, EarlyView.
In the CA1, microglia are activated to be responsible for synaptic pruning. However, LPS induces a senescent phenotype in microglia, characterized by the elevated levels of p16, as well as the production of SASPs. These senescent microglia mediate the removal of excitatory synapses selectively, resulting in dendritic spine loss and LTP impairment ...
Kai Liu, Di Fan, Hai‐peng Wu, Xiao‐yi Hu, Qiu‐li He, Xin‐miao Wu, Cui‐na Shi, Jian‐jun Yang, Mu‐huo Ji   +8 more
wiley   +1 more source

Haplotypes vs single marker linkage disequilibrium tests: what do we gain? [PDF]

, 2001
Joshua M. Akey, Jin Li, Momiao Xiong
openalex   +1 more source

Habitat Quality and Water Availability Affect Genetic Connectivity of Platypus Across an Urban Landscape

Animal Conservation, EarlyView.
We developed a set of innovative landscape resistance models to identify how climatic, topographic and vegetation variables influenced gene flow in the iconic Australian platypus across a 300 km2 urbanised landscape. Our research identified topographic wetness, rainfall and vegetation cover as consistently important for maintaining landscape‐scale gene
Tamielle Brunt, Annabel L. Smith
wiley   +1 more source

The Impact of Patterns in Linkage Disequilibrium and Sequencing Quality on the Imprint of Balancing Selection. [PDF]

Genome Biol Evol
Hayeck TJ, Li Y, Mosbruger TL, Bradfield JP, Gleason AG, Damianos G, Shaw GT, Duke JL, Conlin LK, Turner TN, Fernández-Viña MA, Sarmady M, Monos DS.   +12 more
europepmc   +1 more source

Recovering Power in Association Mapping Panels with Variable Levels of Linkage Disequilibrium

Genetics, 2014
R. Rincent, L. Moreau, H. Monod, E. Kuhn, A. Melchinger, R. Malvar, J. Moreno-González, S. Nicolas, D. Madur, V. Combes, F. Dumas, T. Altmann, D. Brunel, M. Ouzunova, P. Flament, P. Dubreuil, A. Charcosset, T. Mary-Huard   +17 more
semanticscholar   +1 more source