Results 271 to 280 of about 186,640 (297)

Single‐Step Genome‐Wide Association Study of Factors for Evaluated and Linearly Scored Traits in Swedish Warmblood Horses

open access: yesJournal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Swedish Warmblood horses (SWB) are bred for show jumping and/or dressage with young horse test scores as indicator traits. This study aimed to investigate possible candidate genes and regions of importance for evaluated and linearly scored young horse test traits.
Anahit Nazari‐Ghadikolaei   +4 more
wiley   +1 more source

Single‐Step Breeding Value Estimations and Optimum Contribution Selection in Endangered Dual‐Purpose German Black Pied Cattle (DSN) Using a Breed Specific SNP Chip

open access: yesJournal of Animal Breeding and Genetics, EarlyView.
ABSTRACT The aims of the present study were to perform single‐step genomic predictions in the dual‐purpose German Black Pied cattle (DSN) breed considering a DSN specific SNP chip (DSN_200 K), and to use the corresponding estimated breeding values (EBV) in ongoing optimum genetic contribution (OGC) selection.
M. Wolf   +5 more
wiley   +1 more source

A Similarity Matrix for Preserving Haplotype Diversity Amongst Parents in Genomic Selection

open access: yesJournal of Animal Breeding and Genetics, EarlyView.
ABSTRACT In genomic selection, balancing genetic gain with the preservation of genetic diversity is a critical challenge, requiring innovative approaches to parent selection. Traditional methods risk losing valuable genetic diversity by not fully accounting for the complex patterns of haplotype distribution.
Abdulraheem A. Musa, Norbert Reinsch
wiley   +1 more source

An Increase in Male Recombination Rate With Age in Dairy Cattle Is Heritable and Polygenic

open access: yesJournal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Meiotic recombination is an essential process for shuffling genetic diversity in sexually reproducing organisms, can vary within and between individuals in response to intrinsic and extrinsic factors, and can be heritable. Interestingly, recombination rate has been found to vary with age in some species, but to date, there have been no ...
Evelyn Jade   +5 more
wiley   +1 more source

Genomic Signatures of Ancient Vicariance in Host‐Specific Fungal Endophytes Across the Soltis Line in the Pacific Northwest

open access: yesJournal of Biogeography, Volume 52, Issue 7, July 2025.
ABSTRACT Aim Foliar fungal endophytes are a highly diverse component of most plants, both in terms of taxonomic composition and function. Investigating the biogeography of these microbial symbionts in well‐studied regions complements our understanding of the patterns and processes already inferred for animals and plants.
Rodolfo Salas‐Lizana   +2 more
wiley   +1 more source

A Mendelian randomization study on the causal association of circulating cytokines with diabetic nephropathy

open access: yesJournal of Diabetes Investigation, EarlyView.
We performed a two‐sample MR analysis to investigate the causal relationship between circulating cytokines and DN in individuals of European ancestry. We found evidence to support the causal role of genetically predicted circulating levels on the increased risk of DN, including interferon‐gamma, stem cell factor, and stromal‐cell‐derived factor 1 alpha,
Yiming Xu   +5 more
wiley   +1 more source

Association of the IL‐6R rs2228145 polymorphism with diabetic nephropathy: A case‐control study

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Introduction The pathogenesis of diabetes mellitus (DM) and its complications has been previously linked to elevated levels of interleukin‐6 (IL‐6); IL‐6 triggers intracellular pathways through interaction with the IL‐6 receptor (IL‐6R). This study aimed to determine the association of single nucleotide polymorphisms (SNPs) IL‐6 −597G/A ...
Pavla Izakovicova   +7 more
wiley   +1 more source

Genetic analysis of the correlation between GLP1 action and metabolic liver disease: Insights from Mendelian randomization analysis

open access: yesJournal of Diabetes Investigation, EarlyView.
Our study provides genetic analysis supporting the beneficial effects of GLP1 action on MASLD. These benefits may be attributed to mechanisms such as lowering blood glucose levels, reducing blood pressure, and improving HDL cholesterol levels. ABSTRACT Purpose Previous studies have shown that glucagon‐like peptide 1 (GLP1) receptor agonists may help ...
Zhiqiang Ma   +3 more
wiley   +1 more source

Prematuration differences in male and female Atlantic cod: Investigating sex ratio, length and ecotype disparities in juveniles

open access: yesJournal of Fish Biology, EarlyView.
Abstract Sexual size dimorphism (SSD) and skewed sex ratios are common in the animal kingdom, and marine fishes, such as the Atlantic cod (Gadus morhua), are no exception. This study utilized newly discovered sex‐linked genetic markers to investigate young‐of‐the‐year cod in the Skagerrak system, comprising approximately 2700 individuals from North Sea
Sander Vollmerhaus Digre   +4 more
wiley   +1 more source

Low genetic variation and strong genetic structure across a range of geographical scales in European smelt (Osmerus eperlanus L.)

open access: yesJournal of Fish Biology, EarlyView.
Abstract Populations of anadromous European smelt (Osmerus eperlanus L.) are declining across its range with mitigation efforts for this ecologically important species hindered by a lack of demographic information. Here, mitochondrial DNA (mtDNA) and microsatellite analyses were used to describe historical and recurrent demographics for the species ...
Niall J. McKeown   +6 more
wiley   +1 more source

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