Results 271 to 280 of about 199,519 (335)

Exonic Variation in HLA‐C, CFB, and TAP2 Associated With Increased Risk for Comorbid Crohn's Disease and Psoriasis

International Journal of Dermatology, EarlyView.
Our recent work established an association between high polygenic risk scores (PRSes) for both psoriasis and Crohn's disease with the development of comorbid disease. The protein‐coding genetic variation associated with the development of comorbid psoriasis and Crohn's disease is understudied.
Vikram R. Shaw, Jinyoung Byun, Catherine Zhu, Jared Sninsky, Younghun Han, Jeffrey M. Cohen, Christopher I. Amos   +6 more
wiley   +1 more source

The Impact of Patterns in Linkage Disequilibrium and Sequencing Quality on the Imprint of Balancing Selection. [PDF]

Genome Biol Evol
Hayeck TJ, Li Y, Mosbruger TL, Bradfield JP, Gleason AG, Damianos G, Shaw GT, Duke JL, Conlin LK, Turner TN, Fernández-Viña MA, Sarmady M, Monos DS.   +12 more
europepmc   +1 more source

Genetic Determinants of Peanut‐Specific IgG4 Levels in the Context of Sustained Oral Peanut Exposure in the LEAP Study

Immunology, EarlyView.
A cumulative genetic score based on IgG4‐associated variants explains a substantial proportion of variance in psIgG4 levels during sustained peanut consumption, highlighting strong gene‐by‐environment interactions. Our findings suggest that early, sustained peanut consumption, in combination with genetic factors, promotes a protective immune response ...
Kanika Kanchan, Karen Cerosaletti, James A. Perry, George DuToit, Monali Manohar, Hua Ling, Justin E. Paschall, Srinath Sanda, R. Sharon Chinthrajah, Gerald T. Nepom, Kari C. Nadeau, Stacie M. Jones, Gideon Lack, Ingo Ruczinski, Rasika A. Mathias   +14 more
wiley   +1 more source

Probability of linkage disequilibrium for pairs of loci per population of Schistosoma mansoni generated by Arlequin 3.5.2.2.

Karina Varella (12868990), Rosana Gentile (3361136), Roberto do Val Vilela (22032766), Silvana Carvalho Thiengo (5836874), Aline dos Santos Moreira (17203549), José Roberto Machado-Silva (10735253), Thiago dos Santos Cardoso (22032769), Sócrates Fraga da Costa-Neto (12868996), Beatriz de Lima Alessio Müller (22032772), Alexandre Araujo Cunha dos Santos (17011776), Arnaldo Maldonado Junior (22032775)   +10 more
openalex   +1 more source

Moral Distress Among Family Caregivers: A Concept Analysis

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To examine and define the concept of moral distress among family caregivers by identifying its key attributes, antecedents and consequences. Design Concept analysis. Methods This study was guided by Walker and Avant's concept analysis framework.
Tharaa Ananzeh, Caroline F. Morrison, Elaine L. Miller, Natalie Kreitzer, Tamilyn Bakas   +4 more
wiley   +1 more source

Herança genética e desequilíbrio de ligação em locos de isoenzimas em Esenbeckia leiocarpa. Genetic inheritance and linkage disequilibrium in isozymes loci of Esenbeckia leiocarpa.

, 2004
Carlos Eduardo Sícole SEOANE, Alexandre Magno SEBBENN   +1 more
openalex   +1 more source

Genomic Prediction Ability for Novel Profitability Traits Using Different Models in Nelore Cattle

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT The aim of this study was to assess the accuracy, bias and dispersion of genomic predictions for accumulated profitability (APF) and profit per kilogram of liveweight gain (PFT) in Nelore cattle using different prediction approaches. The dataset consisted of 3969 phenotypic records for each trait. The pedigree harboured information from 38,930
Letícia Silva Pereira, Cláudio Ulhôa Magnabosco, Guilherme Rosa, Nedenia Bonvino Stafuzza, Tiago Zanett Albertini, Minos Carvalho, Raysildo Barbosa Lobo, Elisa Peripolli, Eduardo da Costa Eifert, Fernando Baldi   +9 more
wiley   +1 more source

Single‐Step Genomic Predictions for Growth and Carcass Traits in Nordic Charolais and Hereford Cattle

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT In order to investigate the applicability and efficiency of genomic selection for growth and carcass traits in Nordic beef cattle, single‐step genomic BLUP (ssGBLUP) was applied in 4321 Charolais and 4532 Hereford animals with information on approximately 43,000 SNPs each.
Anahit Nazari‐Ghadikolaei, Freddy Fikse, Susanne Eriksson   +2 more
wiley   +1 more source

The Direction of Linkage Disequilibrium: A New Measure Based on the Ancestral-Derived Status of Segregating Alleles

, 2008
K. Ryo Takahasi, Hideki Innan
openalex   +1 more source

Genomic Prediction and Genome‐Wide Association Analysis of Heat Tolerance for Milk Yield in Buffaloes Using a Reaction Norm Model

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT The aim of this study was to evaluate the impact of incorporating genomic information on the estimation of genetic (co)variance components and the accuracy of breeding values for milk yield under varying thermal environments, and to identify SNPs associated with genes that play significant roles in heat tolerance.
Gabriela Stefani, Mário Luiz Santana, Lenira El Faro, Humberto Tonhati   +3 more
wiley   +1 more source