Results 91 to 100 of about 2,105,476 (389)

Estimation of linkage disequilibrium in a sample of the United Kingdom dairy cattle population using unphased genotypes [PDF]

open access: yes, 2003
The association between genetic marker alleles was estimated for two regions of the bovine genome from a random sample of 50 young dairy bulls born in the United Kingdom between 1988 and 1995. Microsatellite marker genotypes were obtained for six markers
Knott, S A   +5 more
core  

Segregation and genetic linkage analyses of river catfish, Mystus nemurus, based on microsatellite markers [PDF]

open access: yes, 2013
The river catfish Mystus nemurus is an important fresh water species for aquaculture in Malaysia. We report the first genetic linkage map of M. nemurus based on segregation analysis and a linkage map using newly developed microsatellite markers of M ...
Hoh, Boon Peng   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Molecular mapping of important agro-botanic traits in sesame [PDF]

open access: yesElectronic Journal of Plant Breeding, 2014
Sesame (Sesamum indicum L.) ((2n=26) is one of the most ancient oilseed crop of the world. The present study was undertaken to develop a molecular map of the important agro-botanic traits in sesame.
P. Venkata Ramana Rao, & , K. Prasuna, G. Anuradha, A. Srividya, Lakshminarayana R Vemireddy, V. Gouri Shankar, S. Sridhar, M. Jayaprada, K. Raja Reddy, N.P. Eswara Reddy and E.A. Siddiq
doaj  

Mapping QTLs for mineral accumulation and shoot dry biomass under different Zn nutritional conditions in Chinese cabbage ( Brassica rapa L. ssp. pekinensis ) [PDF]

open access: yes, 2008
Chinese cabbage (Brassica rapa L. ssp. pekinensis) is one of the most important vegetables in China. Genetic dissection of leaf mineral accumulation and tolerance to Zn stress is important for the improvement of the nutritional quality of Chinese cabbage
Aarts, M.G.M.   +10 more
core   +2 more sources

An ultra-high density linkage map and QTL mapping for sex and growth-related traits of common carp (Cyprinus carpio)

open access: yesScientific Reports, 2016
High density genetic linkage maps are essential for QTL fine mapping, comparative genomics and high quality genome sequence assembly. In this study, we constructed a high-density and high-resolution genetic linkage map with 28,194 SNP markers on 14,146 ...
Wenzhu Peng   +10 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

A multilocus likelihood approach to joint modeling of linkage, parental diplotype and gene order in a full-sib family

open access: yesBMC Genetics, 2004
Background Unlike a pedigree initiated with two inbred lines, a full-sib family derived from two outbred parents frequently has many different segregation types of markers whose linkage phases are not known prior to linkage analysis. Results We formulate
Cui Yuehua, Lu Qing, Wu Rongling
doaj   +1 more source

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