Results 241 to 250 of about 565,196 (323)

Ageism in Rheumatology: The Health Care Professional's Perspective

Arthritis Care &Research, EarlyView.
Objective Ageism (age‐based stereotypes, prejudice, or discrimination) is prevalent and linked to prolonged disability and reduced lifespan in older adults. Little is known about ageism within rheumatology. This study explores the health care professional's (HCP) perception of the care of older adults and how ageist attitudes or perspectives may impact
Aaron P. Smith, Pooja M. Achanta, Jiha Lee, Namrata Singh, Una E. Makris   +4 more
wiley   +1 more source

Biomimetic rigid-soft finger design for highly dexterous and adaptive robotic hands. [PDF]

Sci Adv
Zhang N, Zhou P, Yang X, Shen F, Ren J, Hou T, Dong L, Bian R, Wang D, Gu G, Zhu X.   +10 more
europepmc   +1 more source

Moderators and mediators of pain and function outcomes in a new service delivery model for management of knee osteoarthritis in primary care (PARTNER): Secondary exploratory analysis of a randomized controlled trial

Arthritis Care &Research, Accepted Article.
Objective Explore moderators and mediators influenced changes in pain and function in people with knee osteoarthritis (OA) receiving a new model of primary care service delivery (PARTNER), at 12 months (ACTRN12617001595303). Methods Secondary analyses of a cluster randomized controlled trial comparing PARTNER to usual general practitioner‐delivered ...
Abdolhay Farivar, Jocelyn L Bowden, Kim L Bennell, Andrew M Briggs, Stephen J Bunker, Rana S Hinman, Thorlene Egerton, Simon D French, Marie Pirotta, Karen Schuck, Venkatesha Venkatesha, Nicholas A Zwar, David J Hunter   +12 more
wiley   +1 more source

Tools and challenges in the use of routine clinical data for antimicrobial resistance surveillance. [PDF]

NPJ Antimicrob Resist
Holt KE, Carey ME, Chandler C, Cross JH, Dyson ZA, Furnham N, Glover RE, Virgo M, Knight GM.   +8 more
europepmc   +1 more source

Association Between Sleep Disturbance and Subsequent Pain Interference in Patients With Early Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective This study investigated whether sleep disturbance can predict the extent to which pain interferes with daily functioning in patients with early rheumatoid arthritis (RA). Methods Data were from adults with early RA (joint symptoms ≤12 months) enrolled in the Canadian Early Arthritis Cohort between 2016 and 2023.
Burcu Aydemir, Orit Schieir, Marie‐France Valois, Lutfiyya N. Muhammad, Jing Song, Dorothy Dunlop, Rowland W. Chang, Susan J. Bartlett, Louis Bessette, Gilles Boire, Glen Hazlewood, Carol Hitchon, Janet Pope, Carter Thorne, Diane Tin, Vivian P. Bykerk, Yvonne C. Lee   +16 more
wiley   +1 more source

Gaining insights into genomic regions associated with <i>Chilo partellus</i> resistance in teosinte-derived maize population. [PDF]

Front Genet
Kaur R, Kaur G, Navpreet, Ashmita, Jindal J, Kumar R, Kumar P, Vikal Y, Sharma P.   +8 more
europepmc   +1 more source

Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib

ACR Open Rheumatology, EarlyView.
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi, Ennio Giulio Favalli, Gabriella Maioli, Elena Agape, Marzia Rossato, Matteo Paini, Adriana Severino, Barbara Vigone, Martina Biggioggero, Elena Trombetta, Roberto Caporali, Lorenzo Beretta   +11 more
wiley   +1 more source

Integrative multi-omics investigation of sleep apnea: gut microbiome metabolomics, proteomics and phenome-wide association study. [PDF]

Nutr Metab (Lond)
Wei S, Shen R, Lu X, Li X, He L, Zhang Y, Huang X, Shu Z.   +7 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Integrative QTL Mapping and Transcriptomic Profiling to Identify Growth-Associated QTL and Candidate Genes in Hong Kong Catfish (<i>Clarias fuscus</i>). [PDF]

Animals (Basel)
Zhu Y, Zhou D, Shen Y, Pan C, Chen Y, Zhang Y, Yang B, Li G, Chen H, Tian C.   +9 more
europepmc   +1 more source