Results 191 to 200 of about 174,353 (266)

Bisecting βGlcNAc: MA'AT analysis of ¹³C-labeled oligosaccharides containing βGlcNAc-(1→4)-βMan O-glycosidic linkages. [PDF]

J Biol Chem
Zhang W, Meredith RJ, Lin J, Yoon MK, Carmichael I, Serianni AS.   +5 more
europepmc   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Lignonaut: designing diverse combinatorial libraries for the exploration and annotation of lignin oligomer spaces. [PDF]

J Cheminform
Norberg M, Sandahl M, Spégel P.
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Dissecting PGE₂-driven inhibition of T cell activation using single-cell multi-omic and inflammatory bowel disease genetic association analysis. [PDF]

Nat Commun
Xu Z, Tao S, Feng S, Ye X, Wang T, Hu H, Heidrich-O'Hare E, Chen W, Duerr RH.   +8 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Extending the boundaries of care: Collaboratively planning connections between rehabilitation and community resources for chronic pain self-management. [PDF]

Can J Pain
George NC, Laplante X, Giroux CM, Lemyze C, Lussier M, Leblanc MN, Quesnel-Vallée A, Boivin A, Ahmed S.   +8 more
europepmc   +1 more source