Exploring Linkages between Industrial Innovation and Public Policy: Challenges and Opportunities
Rakesh Basant
doaj +1 more source
Degradable Acrylate-Telechelic Copolymers with Disulfide and β-Thioester Linkages by Simultaneous Thiol Oxidation and Thiol-Ene Michael Addition Click Reactions with the Same Base Catalyst. [PDF]
Szabó Á +5 more
europepmc +1 more source
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Fabrication of healable and flame-retardant polymer films based on phosphonate dynamic covalent crosslinking networks. [PDF]
Maeda K, Okuno Y, Iwasaki Y.
europepmc +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Integrating mortality surveillance as a routine component of national essential public health functions: a blueprint for action. [PDF]
Nichols E +13 more
europepmc +1 more source
The multifaceted roles of lysosomes in cancer
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Linkages and distance geometry. I: Linkages
openaire +2 more sources
Phylogenetic inconsistency of pairwise SNP clustering for inferring tuberculosis transmission in a high-burden, endemic setting: a case study from Thailand. [PDF]
Aiewsakun P +2 more
europepmc +1 more source

