Results 141 to 150 of about 6,889,427 (279)

To SCRY Linked Data

CEUR Workshop Proceedings, 2015
Scientific communities are increasingly publishing datasets on the Web following the Linked Data principles, storing RDF graphs in triplestores and making them available for querying through SPARQL. However, solving domain-specific problems often relies on information that cannot be included in such triplestores. For example, it is virtually impossible
Stringer, Bas, Meroño-Peñuela, Albert, Loizou, Antonis, Abeln, Sanne, Heringa, Jaap   +4 more
openaire   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Linked data storage using DNA origami nanostructures. [PDF]

Nat Commun
Zhang C, Xie M, Wang L, Fan C, Chao J.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A data migration and integration approach for big data management using linked data. [PDF]

Sci Rep
Sattar H, Al-Khasawneh MA, Shafi UF, Hussain T, Saudagar AKJ, Ul Abideen SZ, Kamal MM, Jahfar Khan SB.   +7 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Impact of bariatric surgery on monthly earnings and employment: a national linked data study in England, 2014-2022. [PDF]

Int J Obes (Lond)
Bermingham CR, Ayoubkhani D, Zaccardi F, Coulman KD, Valabhji J, Khunti K, Pournaras DJ, Santos R, Islam N, Razieh C, Dolby T, Nafilyan V.   +11 more
europepmc   +1 more source

Linked Data

IEICE Communications Society Magazine, 2013
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Prediagnostic primary care consultations and imaging in emergency-diagnosed versus referred patients with lung cancer: a population-based linked data study. [PDF]

Br J Gen Pract
Berglund M, White B, Barclay ME, Whitfield E, Renzi C, Rafiq M, Navani N, Thompson CA, Lyratzopoulos G.   +8 more
europepmc   +1 more source