Results 121 to 130 of about 3,423,786 (296)

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Linked Open Government Data: Still a Viable Option for Sharing and Integrating Public Data?

Future Internet
Linked Data (LD) principles, when applied to Open Government Data (OGD), aim to make government data accessible and interconnected, unlocking its full potential and facilitating widespread reuse.
Alfonso Quarati, Riccardo Albertoni
doaj   +1 more source

End-user data-centric interactions over linked data

, 2013
The ability to build tools that support gathering and querying information from distributed sources on the Web rests on the availability of structured data.
Popov, Igor
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Linked Timelines: Temporal Representation and Management in Linked Data

This paper addresses the issue of representing time entities (i.e. instants and intervals) as Linked Data, and how to exploit topological temporal relationships in order to increase the connectivity degree within Linked Data sets.
Millard, Ian, Correndo, Gianluca, Salvadores, Manuel, Shadbolt, Nigel   +3 more
core  

Evaluation a of a layered approach to question answering over linked data

, 2012
Walter S, Unger C, Cimiano P, Bär D. Evaluation a of a layered approach to question answering over linked data. Presented at the The 11th International Semantic Web Conference (ISWC 2012), Boston, USA.We present a question answering system architecture ...
Christina Unger, Philipp Cimiano, Bär, Daniel, Daniel Bär, Walter, Sebastian, Sebastian Walter, Cimiano, Philipp, Walter, Sebastian ; https://orcid.org/, Unger, Christina ; https://orcid.org/, Unger, Christina, Cimiano, Philipp ; https://orcid.org/   +10 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Addressing Dementia Through Analysis of Population Traits and Risk Factors (ADAPTOR) project: dementia incidence in an Australian cohort

Public Health Research & Practice, 2023
Smriti Nepal , Xenia Dolja-Gore, Dominic Cavenagh , Catherine D'Este , Kaarin J Anstey, Henry Brodaty , Heidi J Welberry, Anita MY Goh , Martin McNamara   +8 more
doaj   +1 more source

Provenance in Linked Data Integration

, 2010
The open world of the (Semantic) Web is a global information space offering diverse materials of disparate qualities, and the opportunity to re-use, aggregate, and integrate these materials in novel ways. The advent of Linked Data brings the potential to
Gibbins, Nicholas, Omitola, Temitope, Shadbolt, Nigel   +2 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source