Results 111 to 120 of about 3,423,786 (296)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
A comprehensive quality model for Linked Data
, 2018 With the increasing amount of Linked Data published on the Web, the community has recognised the importance of the quality of such data and a number of initiatives have been undertaken to specify and evaluate Linked Data quality.
Mihindukulasooriya, Nandana +3 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Using SPARQL to access Linked Open Data
The Programming Historian, 2015 This lesson explains why many cultural institutions are adopting graph databases, and how researchers can access these data though the query language called SPARQL.
Matthew Lincoln
doaj
The growth of the Linked Data corpus will eventually pre- vent all but the most determined of consumers from including every Linked Dataset in a single undertaking.
Gibbins, Nicholas +3 more
core
Linked data for accessibility: from techniques to users
, 2013 The advanced characteristics of Linked Data drive the dramatic growth of accessible public data. With very few accessibility research projects applying Linked Data , this paper reviews the challenges of accessibility and proposes the approach to use ...
Ding, Chaohai, Wald, Mike, Wills, Gary
core
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
ISPRS International Journal of Geo-InformationThe Web of Data has been fueled significantly by geospatial data over the last few years. In the current link discovery frameworks, there is still a lack of robust support for finding geospatial-aware links between geospatial data sources in the Web of ...
Lianlian He, Ruixiang Liu
doaj +1 more source
Publishing Linked Data - There is no One-Size-Fits-All Formula
, 2012 Publishing Linked Data is a process that involves several design decisions and technologies. Although some initial guidelines have been already provided by Linked Data publishers, these are still far from covering all the steps that are necessary (from ...
Vila-Suero, Daniel +7 more
core