Results 91 to 100 of about 28,046,348 (280)
IEEE Transactions on Nuclear Science, 1991 The authors report on the design and performance of high-speed data links and slower configuration control links used between the EOS TPC (Equation-of-State Time Projection Chamber) detector and the data processing electronics. Data rates of 5 Mb/s are maintained over 30 m with optical isolation. Pedestal subtraction, hit detection, and data reordering
Bieser, F., Jones, R., McParland, C.
openaire +2 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
The growth of the Linked Data corpus will eventually pre- vent all but the most determined of consumers from including every Linked Dataset in a single undertaking.
Gibbins, Nicholas +3 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Linked Heritage training programme: Learning objects
, 2013 A set of learning objects produced by the University Libraries Centre (Centro d\u27 Ateneo per le Biblioteche - CAB) of Padua University in collaboration with participants of the Linked Heritage international Working Group on training (WP7).
core
Integrating public datasets using linked data: challenges and design principles
, 2010 The world is moving from a state where there is paucity of data to one of surfeit. These data, and datasets, are normally in different datastores and of different formats.
Hall, Wendy +7 more
core +1 more source