Results 101 to 110 of about 3,440,234 (310)

A Study of Linked Open Data Life Cycles [PDF]

, 2017
Artigo apresentado no I Workshop de Informação, Dados e Tecnologia, realizado entre nos dias 04 e 06 de setembro de 2017, na cidade de Florianópolis (SC), no Auditório do Espaço Físico Integrado (EFI) da Universidade Federal de Santa Catarina (UFSC ...
Gomes, Murilo Silveira, Todesco, José Leomar, Visintin, Lidiane   +2 more
core  

Indonesia COVID-19 cases report using Linked Open Data. [PDF]

Procedia Comput Sci, 2022
Rahkmawati NA, Akbar A, Adhilaksono B, Baharuddin F, Hidayat R.   +4 more
europepmc   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

FEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo   +10 more
wiley   +1 more source

Building ontologies from folksonomies and linked data: Data structures and Algorithms [PDF]

, 2012
We present the data structures and algorithms used in the approach for building domain ontologies from folksonomies and linked data. In this approach we extracts domain terms from folksonomies and enrich them with semantic information from the Linked ...
Corcho, Oscar, García-Castro, Alexander, García-Castro, Leyla Jael, García-Silva, A., Gómez-Pérez, A.   +4 more
core   +1 more source

An empirical meta-analysis of the life sciences linked open data on the web. [PDF]

Sci Data, 2021
Kamdar MR, Musen MA.
europepmc   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

Why Geospatial Linked Open Data for Smart Mobility? [PDF]

, 2016
While the concept of Smart Cities is gaining momentum around the world and government data are increasingly available and accessible on the World Wide Web, key issues remain about Open Data and data standards for smart cities.
Dangol, Anuja, Dewaelheyns, Valerie, Steenberghen, Thérèse   +2 more
core  

Quality Assessment of Linked Datasets using Probabilistic Approximation

, 2015
With the increasing application of Linked Open Data, assessing the quality of datasets by computing quality metrics becomes an issue of crucial importance. For large and evolving datasets, an exact, deterministic computation of the quality metrics is too
A Hogan, AZ Broder, BH Bloom, C Guéret, JS Vitter, P Hitzler   +5 more
core   +1 more source

Apoiando estudos cientométricos com Linked Open Data

Perspectivas em Ciência da Informação
RESUMO Na Cientometria, mensurar indicadores é uma tarefa complexa devido aos desafios em coletar, organizar e relacionar dados, sobretudo, na web, onde os dados são distribuídos em várias fontes e formatos incompatíveis.
Sandro Rautenberg, Edgard Marx, Antonio Costa Gomes Filho, Sören Auer   +3 more
doaj   +1 more source