Results 191 to 200 of about 5,195,087 (380)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

A linked open data representation of patents registered in the US from 2005-2017. [PDF]

Sci Data, 2018
Hassan MM, Zaveri A, Lehmann J.
europepmc   +1 more source

LIBER 2020 - Workshop: LIBER Linked Open Data Working Group – LOD Publication for Libraries

, 2020
Matias Frosterus, Sofia Zapounidou, Tiziana Possemato, Michalis Sfakakis, Andreas Walker, Christos Papatheodorou, Anna Lionetti   +6 more
openalex   +1 more source

A Companion Screen Application for TV Broadcasts Annotated with Linked Open Data [PDF]

, 2014
Lyndon Nixon, Lotte Belice Baltussen, Lilia Pérez Romero, Lynda Hardman   +3 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Francesca Di Donato, Lo stato trasparente. Linked Open Data e cittadinanza attiva

Bollettino Telematico di Filosofia Politica, 2011
Il libro, liberamente scaricabile a partire da qui,  presenta un’istantanea di un fenomeno recente: il movimento Open Government Data. Questo movimento trae ispirazione dal software libero e della pubblicazione ad accesso aperto, fondate entrambi sulla ...
Maria Chiara Pievatolo
doaj  

Linked Open Data and e-Participation in the EU Law-Making Process

, 2016
Peter Schmitz, Enrico Francesconi, Brahim Batouche, B. Dombrovschi, Du Nguyen Duy, S. P. Landercy, V. Parisse   +6 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Database Release: PPSDB, a Linked Open Data Knowledge Base for Protist-Prokaryote Symbioses. [PDF]

J Eukaryot Microbiol
Seah BKB.
europepmc   +1 more source

Fully connecting the Observational Health Data Science and Informatics (OHDSI) initiative with the world of linked open data. [PDF]

Genomics Inform, 2019
Banda JM.
europepmc   +1 more source