Results 201 to 210 of about 1,479,186 (249)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Prevalence of self-harm across urgent and emergency care settings among young people and factors associated with reattendance: protocol for a prospective cohort study. [PDF]

BMJ Open
Romeu D, Relton S, Burton C, Crum A, Chambers EV, Cottrell D, Guthrie E.   +6 more
europepmc   +1 more source

Mental health peer support relationship: a realist informed qualitative meta synthesis. [PDF]

BMJ Open
Hackmann C, Green A, Pease R, Clegg I, Handley M.   +4 more
europepmc   +1 more source

Editorial Comment on Comparison of Perioperative Chemotherapy Regimens for Muscle-Invasive Bladder Cancer: A Reconstructed Individual Patient Data Analysis of Phase 3 Trials. [PDF]

Int J Urol
Goto Y.
europepmc   +1 more source

Complex system structures around drug-related deaths in Scotland: a mixed method network analysis approach to study subsystems in population data and system maps

McCann M, Seaman R, Letina S, Parkes T, Barnsdale L, Matheson C, Schofield J, Hilton J, Baldacchino A, Crofton A, Skivington K.   +10 more
europepmc   +1 more source

Linked Open Library Data

, 2010
openaire   +1 more source