Results 241 to 250 of about 3,440,234 (310)

Linked open data for halal food products

, 2019
Nur Aini Rakhmawati, Jauhar Fatawi, Ahmad Najib, Azmi Adi Firmansyah   +3 more
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Surgery or radiotherapy for early-stage cancer study (SORT) target trial protocol: stereotactic ablative radiotherapy (SABR) with curative intent versus surgical resection for early-stage non-small cell lung cancer (NSCLC). [PDF]

BMJ Open
Kagenaar E, Lugo-Palacios DG, Hutchings A, Aggarwal A, O'Neill S, Rachet B, Edwards J, Faivre-Finn C, Grieve R, Surgery or Radiotherapy Study (SORT) group.   +9 more
europepmc   +1 more source

Exposing French agronomic resources as Linked Open Data

, 2016
Aravind Venkatesan, Nordine El Hassouni, Florian Philippe, Cyril Pommier, Hadi Quesneville, Manuel Ruíz, Pierre Larmande   +6 more
openalex   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Prognostic factors associated with failure of total elbow replacement: a protocol for analysis of National Joint Registry data in England. [PDF]

BMJ Open
Hamoodi Z, Sayers A, Whitehouse MR, Kearsley-Fleet L, Sergeant JC, Watts AC.   +5 more
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Primary care patients presenting with unexpected weight loss in Australian general practices: replication of a diagnostic accuracy study. [PDF]

BMJ Open
Lee A, de Mendonça L, McCarthy D, Nelson C, Rafiq M, Venning B, Chima S, Daly D, Fishman G, Kearney C, Hunter B, Lim FS, Manski-Nankervis JA, Nicholson BD, Emery J, Martinez-Gutierrez J.   +15 more
europepmc   +1 more source