Results 91 to 100 of about 4,098,264 (291)

Thermoelectric efficiency of single-molecule junctions with long molecular linkers

open access: yes, 2018
We report results of theoretical studies of thermoelectric efficiency of single-molecule junctions with long molecular linkers. The linker is simulated by a chain of identical sites described using a tight-binding model.
Zimbovskaya, Natalya A.
core   +1 more source

Selective ring-opening metathesis polymerization (ROMP) of cyclobutenes. Unsymmetrical ladderphane containing polycyclobutene and polynorbornene strands

open access: yesBeilstein Journal of Organic Chemistry, 2019
At 0 °C in THF in the presence of Grubbs first generation catalyst, cyclobutene derivatives undergo ROMP readily, whereas norbornene derivatives remain intact. When the substrate contains both cyclobutene and norbornene moieties, the conditions using THF
Yuan-Zhen Ke   +3 more
doaj   +1 more source

Statistical mechanics of nucleosome ordering by chromatin structure-induced two-body interactions

open access: yes, 2011
One-dimensional arrays of nucleosomes (DNA-bound histone octamers separated by stretches of linker DNA) fold into higher-order chromatin structures which ultimately make up eukaryotic chromosomes.
Chereji, Răzvan V.   +3 more
core   +1 more source

The Link That Binds: The Linker of Hsp70 as a Helm of the Protein’s Function

open access: yesBiomolecules, 2019
The heat shock 70 (Hsp70) family of molecular chaperones plays a central role in maintaining cellular proteostasis. Structurally, Hsp70s are composed of an N-terminal nucleotide binding domain (NBD) which exhibits ATPase activity, and a C-terminal ...
Graham Chakafana   +2 more
doaj   +1 more source

Albumin-Binding PSMA Radioligands: Impact of Minimal Structural Changes on the Tissue Distribution Profile

open access: yesMolecules, 2020
The concept of using ibuprofen as an albumin-binding entity was recently demonstrated by the development of [177Lu]Lu-Ibu-PSMA-01. In the present study, we designed a novel ibuprofen-containing radioligand (Ibu-PSMA-02) with subtle structural changes ...
Luisa M. Deberle   +6 more
doaj   +1 more source

A quantitative investigation of linker histone interactions with nucleosomes and chromatin

open access: yesScientific Reports, 2016
Linker histones such as H1 are abundant basic proteins that bind tightly to nucleosomes, thereby acting as key organizers of chromatin structure. The molecular details of linker histone interactions with the nucleosome and in particular the contributions
Alison E. White, Aaron R Hieb, K. Luger
semanticscholar   +1 more source

Unfolding cross-linkers as rheology regulators in F-actin networks

open access: yes, 2007
We report on the nonlinear mechanical properties of a statistically homogeneous, isotropic semiflexible network cross-linked by polymers containing numerous small unfolding domains, such as the ubiquitous F-actin cross-linker Filamin.
Alex J. Levine   +10 more
core   +1 more source

Predictable Peptide Conjugation Ratios by Activation of Proteins with Succinimidyl Iodoacetate (SIA)

open access: yesMethods and Protocols, 2017
The small heterobifunctional linker succinimidyl iodoacetate (SIA) was examined for the preparation of peptide–protein bioconjugates with predicable conjugation ratios.
Ioana M. Abbas   +3 more
doaj   +1 more source

Theory of Crosslinked Bundles of Helical Filaments: Intrinsic Torques in Self-Limiting Biopolymer Assemblies

open access: yes, 2011
Inspired by the complex influence of the globular crosslinking proteins on the formation of biofilament bundles in living organisms, we study and analyze a theoretical model for the structure and thermodynamics of bundles of helical filaments assembled ...
Grason, Gregory M., Heussinger, Claus
core   +1 more source

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