Results 111 to 120 of about 4,098,264 (291)

Antibody-drug conjugates in cancer therapy: current advances and prospects for breakthroughs

Frontiers in Cell and Developmental Biology
Antibody-drug conjugates (ADCs), often referred to as “intelligent biological missiles,” have garnered significant attention in the rapidly evolving landscape of cancer therapy. ADCs represent a sophisticated approach by integrating monoclonal antibodies
Dan Wu, Dan Wu, Dan Wu, Kaixuan Yang, Kaixuan Yang, Runjia He, Rutie Yin, Rutie Yin, Lin Shui, Lin Shui   +9 more
doaj   +1 more source

HookA is a novel dynein–early endosome linker critical for cargo movement in vivo

Journal of Cell Biology, 2014
HookA is a novel linker protein that binds to endosomes and to dynein–dynactin and promotes dynein–early endosome interaction in Aspergillus.
Jun Zhang, Rongde Qiu, H. Arst, M. Peñalva, Xin Xiang   +4 more
semanticscholar   +1 more source

TRIPHOSPHOPYRIDINE NUCLEOTIDE LINKED ISOCITRIC DEHYDROGENASE IN BACTERIA [PDF]

, 1952
Stanley Barban, S. J. Ajl
openalex   +1 more source

An unprecedented 2D covalent organic framework with an htb net topology. [PDF]

, 2019
A 2D imine-linked COF with a hitherto unreported htb type topology was synthesized from a linear diamine linker and a judiciously designed tetra-aldehyde building block.
Cai, Song-Liang, Fan, Jun, He, Zi-Hao, Li, Xin-Le, Liu, Yi, Zhang, Kai, Zhang, Wei-Guang, Zheng, Sheng-Run   +7 more
core  

Mechanical control of the directional stepping dynamics of the kinesin motor

, 2007
Among the multiple steps constituting the kinesin's mechanochemical cycle, one of the most interesting events is observed when kinesins move an 8-nm step from one microtubule (MT)-binding site to another.
Asenjo, Brady, C. Hyeon, Carter, Coppin, Cross, Dyson, Gilbert, Hancock, J. N. Onuchic, Julicher,, Kaseda, Kolomeisky, Kubelka, Levy, Ma, Moyer, Nishiyama, Onuchic, Ray, Rice, Taniguchi, Thirumalai, Tomishige, Vale, Visscher   +25 more
core   +2 more sources

Linkers for bioconjugation

, 2016
[eng] Cancer is a heterogeneous disease that represents one of the principal causes of mortality in developed countries. Due to the social and economic implications of this pathology, tremendous efforts have been making over the past decades to improve available therapeutic options to tackle this illness.
openaire   +1 more source

Optimizing the Amino Acid Sequence Enhances the Productivity and Bioefficacy of the RBP-Albumin Fusion Protein

Bioengineering
The significant growth of the global protein drug market, including fusion proteins, emphasizes the crucial role of optimizing amino acid sequences to enhance the productivity and bioefficacy.
Ji Hoon Park, Sohyun Kwon, So-Young Choi, Bongcheol Kim, Junseo Oh   +4 more
doaj   +1 more source

Bandgap Engineering on UiO–66 Metal‐Organic Framework Derivatives for Solar‐Driven Seawater Desalination

Advanced Science
The growing scarcity of freshwater, driven by climate change and pollution, necessitates the development of efficient and sustainable desalination technologies. Solar‐powered interfacial water evaporation has emerged as a promising solution; however, its
Qisheng Shao, Yutong Ding, Wenxian Liu, Jia Guan, Ge Meng, Tairong Kuang, Dingsheng Wang   +6 more
doaj   +1 more source

Untersuchungen über die Sekrete. Ueber den Harzbalsam von Picea vulgaris Link. (Jura‐Terpentin.) [PDF]

, 1900
A. Tschirch, Eduardo Bruning
openalex   +1 more source

Zeolitic Imidazolate Frameworks as H_2 Adsorbents: Ab Initio Based Grand Canonical Monte Carlo Simulation [PDF]

, 2010
We report the H_2 uptake behavior of 10 zeolitic−imidazolate frameworks (ZIFs), based on grand canonical Monte Carlo (GCMC) simulations. The force fields (FFs) describing the interactions between H_2 and ZIF in the GCMC were based on ab initio quantum ...
Choi, Seung-Hoon, Goddard, William A., III, Han, Sang Soo   +2 more
core   +1 more source