Results 61 to 70 of about 1,400,039 (300)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Asymmetric critical fractional p-Laplacian problems
We consider the asymmetric critical fractional p-Laplacian problem $$\displaylines{ (-\Delta)^s_p u = \lambda |u|^{p-2} u + u^{p^\ast_s - 1}_+,\quad \text{in } \Omega;\cr u = 0, \quad \text{in } \mathbb{R}^N\setminus\Omega; }$$ where $\lambda>0 ...
Li Huang, Yang Yang
doaj
Bias-Reduced Haebara and Stocking–Lord Linking
Haebara and Stocking–Lord linking methods are frequently used to compare the distributions of two groups. Previous research has demonstrated that Haebara and Stocking–Lord linking can produce bias in estimated standard deviations and, to a smaller extent,
Alexander Robitzsch
doaj +1 more source
Linking Climate Change Adaptation and Mitigation: A Review with Evidence from the Land-Use Sectors
There is extensive scientific evidence that both adaptation and mitigation are essential to address the problem of climate change. However, there is still limited knowledge about the possibilities for exploiting the interrelationships between these ...
Rico Kongsager
doaj +1 more source
Unlinkability is a privacy property of crucial importance for several systems (such as RFID or voting systems). Informally, unlinkability states that, given two events/items in a system, an attacker is not able to infer whether they are related to each other.
Brusó, Mayla +3 more
openaire +5 more sources
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Förster, Manuel +2 more
openaire +4 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

