Results 111 to 120 of about 2,653,759 (281)

1G-20　How useful is linking between error causes in human error analysis?

, 2013
As finding root causes of human error in safety-critical systems is a cognitively demanding and time-consuming task, it is particularly necessary to develop a method for improving both the quality and efficiency of the task.
Kim, Dong San, Yoon, Wan-Chul
core   +1 more source

A Risk-Aware Safety Framework for UWB-Localized Quadrotors: Geometry-Aware Error Compensation and Belief-Space Collision Avoidance

Machines
Ultra-wideband (UWB) positioning provides cost-effective localization for quadrotors in global navigation satellite system (GNSS)-denied environments, but geometry-dependent, heavy-tailed errors challenge state estimation and safety-critical control ...
Yufei Yang, Junjie Cao, Yaohua Shen
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Clinical characteristics and management strategies of keratoconus in iraqi patients

Delta Journal of Ophthalmology
Purpose The aim of this study was to investigate the clinical characteristics, refractive error profile, and management approaches in Iraqi patients diagnosed with keratoconus (KC), emphasizing the disease severity, sex distribution, and visual outcomes.
Shakir M. Lafta, Zaydoon T.M. Noori, Hassan A. Aljaberi, Amel M. Naji, Saeed Rahmani   +4 more
doaj   +1 more source

Surgical Options for the Refractive Correction of Keratoconus: Myth or Reality

Journal of Ophthalmology, 2017
Keratoconus provides a decrease of quality of life to the patients who suffer from it. The treatment used as well as the method to correct the refractive error of these patients may influence on the impact of the disease on their quality of life.
L. Fernández-Vega-Cueto, V. Romano, R. Zaldivar, C. H. Gordillo, F. Aiello, D. Madrid-Costa, J. F. Alfonso   +6 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

A variational framework for residual-based adaptivity in neural PDE solvers and operator learning

npj Artificial Intelligence
Residual-based adaptive strategies are widely used in scientific machine learning yet remain largely heuristic. We introduce a variational framework that formalizes these methods through convex transformations of the residual, where different ...
Juan Diego Toscano, Daniel T. Chen, Vivek Ooomen, Jérôme Darbon, George Em Karniadakis   +4 more
doaj   +1 more source

Calculation of stress-strain relationship of chlorinated polyethylene rubber/nitrile rubber blend by regulating cross-linking density of chlorinated polyethylene rubber phase

Hecheng xiangjiao gongye
Chlorinated polyethylene rubber (CM)/nitrile rubber (NBR) blend vulcanizates were prepared by mechanical blending method with CM and NBR as main raw materials, the cross-linking density of CM phase in CM/NBR blend vulcanizate and the stress-strain ...
SUN Zhen-hao, DENG Tao
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Evaluation of particle tracking codes for dispersing particles in porous media

Scientific Reports
Particle tracking (PT) is a popular technique in microscopy, microfluidics and colloidal transport studies, where image analysis is used to reconstruct trajectories from bright spots in a video.
Marc Berghouse, Filippo Miele, Lazaro J. Perez, Ankur Deep Bordoloi, Verónica L. Morales, Rishi Parashar   +5 more
doaj   +1 more source