Exogenous melatonin induces phenolic compounds production in Linum album cells by altering nitric oxide and salicylic acid [PDF]
Scientific Reports, 2023 Melatonin is a pleiotropic molecule that can influence various aspects of plant performance. Recent studies have exhibited that it mediates plant defensive responses, probably through managing redox homeostasis.
Sara Esmaeili +5 more
doaj +4 more sources
Comprehensive RNA-Seq-based study and metabolite profiling to identify genes involved in podophyllotoxin biosynthesis in Linum album Kotschy ex Boiss. (Linaceae) [PDF]
Scientific Reports, 2023 Linum album is a well-known rich source of anticancer compounds, i.e., podophyllotoxin (PTOX) and other lignans. These compounds play an important role in the plant’s defensive system. The RNA-Seq data of flax (L.
Zahra Danaeipour +4 more
doaj +2 more sources
Physiological, biochemical, and molecular responses of Linum album to digested cell wall of Piriformospora indica. [PDF]
Physiol Mol Biol Plants, 2021 Plants synthesize a variety of metabolites in response to biotic elicitors. To comprehend how the digested cell wall of Piriformospora indica affects the response of ROS burst, antioxidant enzymes, amino acids profiling, and phenylpropanoid compounds such as lignans, phenolic acids, and flavonoids in Linum album hairy roots; we accomplished a time ...
Tashackori H +5 more
europepmc +3 more sources
Changes in MicroRNAs expression mediate molecular mechanism underlying the effect of MeJA on the biosynthesis of podophyllotoxin in Linum album cells [PDF]
Scientific ReportsPodophyllotoxin (PTOX), produced by Linum album, is a monolignol that participates in plant defense strategies. Our previous study established that methyl jasmonate (MeJA) significantly stimulates PTOX production in L. album cells.
Mostafa Sagharyan +3 more
doaj +2 more sources
Antioxidant and metabolic responses of Linum album cell culture to polyethylene glycol-induced drought stress [PDF]
BMC Plant BiologyOwing to drought stress disruptions, the physiological and biochemical homeostasis required for the plants’ growth and productivity is severely compromised. Here, we studied the adaptive mechanisms of Linum album cells exposed to drought stress.
Zahra Akbarifard +2 more
doaj +2 more sources
Regulation of lignan biosynthesis through signaling pathways mediated by H2O2 in Linum album cell culture in response to exogenous putrescine [PDF]
Scientific ReportsPolyamines are small aliphatic amines whose metabolic reprogramming is involved in the regulation of various plant cellular reactions. Our previous study showed that polyamines increased lignan production in Linum album; however, little is known about ...
Elaheh Samari +4 more
doaj +2 more sources
Medical Sciences Forum, 2022 Podophyllotoxin (PTOX), one of the most important natural medicinal compounds, has anticancer properties. Its effective medicinal derivatives, such as etoposide and teniposide, have been approved by the Food and Drug Administration (FDA) for cancer ...
Zahra Danaeipour +4 more
doaj +2 more sources
Effect of Some Phytohormones on Podophyllotoxin Production in Cell and Plantlets Cultures of Linum album [PDF]
Journal of Medicinal Plants and By-products, 2013 The natural lignan podophyllotoxin, a dimerized product of two phenylpropanoid moieties which occurs in a few plant species, is a pharmacologically important compound for its anticancer activities.
Fakhari, Safieh +3 more
doaj +3 more sources
Apoptotic Effects of Linum album Extracts on AGS Human Gastric Adenocarcinoma Cells and ZNF703 Oncogene Expression [PDF]
Asian Pac J Cancer Prev, 2018 Introduction: Linum album is a medicinal plant endemic in Iran that is very important pharmaceutically. The present study concerns the effect of different extracts of L. album on ZNF703 gene expression and apoptosis in human gastric carcinoma AGS cells. Method and material: Hydro alchoholic L.
Akbari Asl E +5 more
europepmc +3 more sources
Induction of defensive responses and production of secondary metabolites in Linum album cell culture by ultrasound [PDF]
Zīst/shināsī-i Giyāhī-i Īrān, 2015 Ultrasound (US) with low intensity is considered as a physical tool to stimulate living systems in medicine and biotechnology. This study aim to survey the US effects on some physiological parameters and podophyllotoxin production in Linum album cell ...
Armaghan Abedzadeh Neyshabouri +1 more
doaj +1 more source