Results 41 to 50 of about 2,921 (250)
Levothyroxine and lung cancer in females: the importance of oxidative stress [PDF]
, 2013 BACKGROUND: Levothyroxine (LT(4)) treatment can lead to iatrogenic hyperthyroidism and oxidative stress that can cause patient discomfort. Oxidative stress is also recognized as one of the causes of chronic diseases and cancer. METHODS: The prevalence of
Annarosa Finco +3 more
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Advanced Healthcare Materials, EarlyView.Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim +5 more
wiley +1 more source
Liothyronine (FK-300) in the Treatment of Male Infertility [PDF]
, 1961 1) L-Triiodothyronine (FK-300) was given to 12 patients of male infertility, 3 of azoospermia and 9 of oligospermia. There was an increase in sperm count observed in 8, a rise in sperm motility in 7, and the wife of the highly oligospermic men conceived.
原, 信二, 石神, 襄次
core
Advanced Healthcare Materials, EarlyView.Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim +4 more
wiley +1 more source
Nanochanneled Device and Related Methods [PDF]
, 2013 A capsule configured for in vivo refilling of a therapeutic agent.
Ferrari, Mauro +4 more
core +5 more sources
The Swinging Pendulum in Treatment for Hypothyroidism: From (and Toward?) Combination Therapy
Frontiers in Endocrinology, 2019 Thyroid hormone replacement for hypothyroidism can be achieved via several approaches utilizing different preparations of thyroid hormones, T3, and/or T4.
Elizabeth A. McAninch, Antonio C. Bianco
doaj +1 more source
Hypothyroidism and mood disorders: integrating novel insights from brain imaging techniques [PDF]
, 2011 Thyroid hormones play a critical role in brain development but also in the adult human brain by modulating metabolic activity. Hypothyroid states are associated with both functional and structural brain alterations also seen in patients with major ...
Maximilian Pilhatsch +4 more
core +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Iodothyronine deiodinases and reduced sensitivity to thyroid hormones
Frontiers in Bioscience-Landmark, 2020 Iodothyronine deiodinases are selenoproteins that regulate thyroid hormone metabolism. Of the three types of deiodinases, type 2 is the major regulator of intracellular triiodothyronine concentration in both the hypothalamus and pituitary, and therefore ...
Rosa Maria Paragliola +6 more
doaj +1 more source
Hypothyroid Crisis: Oral or Intravenous Treatment? A Report of Two Cases
European Journal of Case Reports in Internal Medicine, 2021 Background: Hypothyroid crisis, or myxoedema coma, is a rare condition with high mortality and must be treated promptly. Even though it may be unfavourable, most guidelines only focus on intravenous drug administration due to lack of data on oral ...
Rens Gadaen +1 more
doaj +1 more source