Results 41 to 50 of about 2,262 (235)

Combination Thyroid Hormone Replacement; Knowns and Unknowns

Frontiers in Endocrinology, 2019
Hypothyroidism is common throughout the world and readily diagnosed with thyroid function tests. Management should be straightforward but appears not to be the case.
Peter N. Taylor, Vinay Eligar, Ilaria Muller, Anna Scholz, Colin Dayan, Onyebuchi Okosieme   +5 more
doaj   +1 more source

Hypothyroidism: The difficulty in attributing symptoms to their underlying cause

Frontiers in Endocrinology, 2023
Common symptoms of overt hypothyroidism are non-specific and include fatigue, lethargy, and dry skin. Although the diagnosis is considered to be straightforward, no single symptom can be used to identify patients with overt hypothyroidism, while many ...
Heleen I. Jansen, Heleen I. Jansen, Heleen I. Jansen, Anita Boelen, Anita Boelen, Anita Boelen, Annemieke C. Heijboer, Annemieke C. Heijboer, Annemieke C. Heijboer, Annemieke C. Heijboer, Eveline Bruinstroop, Eveline Bruinstroop, Eric Fliers, Eric Fliers   +13 more
doaj   +1 more source

Successful Oral Levothyroxine Desensitization in a Patient with Severe Hypothyroidism Post Radioactive Iodine Therapy

Journal of the ASEAN Federation of Endocrine Societies, 2022
Levothyroxine remains the standard therapy for patients with hypothyroidism worldwide. Levothyroxine allergy is rarely seen and alternative therapies are less efficacious and scarcely available. The use of liothyronine (LT3) monotherapy is less favoured
Yi Jiang Chua, Bay Shing Shen, Taye Zhi Yun, Carolina Singarayar, Foo Siew Hui   +4 more
doaj   +1 more source

The Swinging Pendulum in Treatment for Hypothyroidism: From (and Toward?) Combination Therapy

Frontiers in Endocrinology, 2019
Thyroid hormone replacement for hypothyroidism can be achieved via several approaches utilizing different preparations of thyroid hormones, T3, and/or T4.
Elizabeth A. McAninch, Antonio C. Bianco
doaj   +1 more source

Iatrogenic Thyrotoxicosis due to Compounding Error of Liothyronine

, 2023
Background: This case is one of four recorded reports of thyrotoxicosis due to compounding error of liothyronine. The presentation of this differs from classic thyrotoxicosis caused by endogenous hormones.
Onyechi, Stephanie, Falkoff, Maxwell
core   +1 more source

Sustained Release T3 Therapy: Animal Models and Translational Applications

Frontiers in Endocrinology, 2019
The standard of care to treat hypothyroidism is daily administration of levo-thyroxine (LT4). This is based on the understanding that deiodinases can restore production of T3 and compensate for the small amounts of T3 that are normally produced by the ...
Thaer Idrees, John D. Price, Thomas Piccariello, Thomas Piccariello, Antonio C. Bianco   +4 more
doaj   +1 more source

Successful treatment of myxedema coma using levothyroxine and liothyronine in the setting of adrenal crisis and severe cardiogenic shock in a patient with apparent primary empty sella

Journal of Clinical and Translational Endocrinology Case Reports, 2021
Hypothyroidism is a common pathological condition of thyroid hormone deficiency that varies widely in relation to both the acuity with which the deficiency develops and the clinical manifestations of the disease.
Omar Elghawy, Alexander C. Hafey, Christopher R. McCartney, Jeremy R. Steinman   +3 more
doaj   +1 more source

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

Advanced Science, EarlyView.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li, Yijun Ge, Jingxiao Du, Liu Yang, Bangsheng Wu, Chenyue Hang, Mengxi Shen, Yimin Mao, Ting Zhang, Qiyu Bo, Tianyuan Zhao, Yutian Jiao, Yazhi Wang, Shunxiang Gao, Jieqiong Chen, Junran Sun, Tong Li, Huixun Jia, Yang Dou, Wei Cheng, Xiaoling Wan, Jintai Yu, Xiaodong Sun, Bai Lu   +23 more
wiley   +1 more source

The determination of liothyronine and thyroxine in thyroid preparations

, 1966
A procedure is described for determining liothyronine and thyroxine in thyroid substances. This involves stepwise hydrolysis with barium hydroxide, extraction of combined iodinated amino-acids by n-butanol, separation and isolation of liothyronine and ...
J M TALMAGE, R LEMIEUX
core   +1 more source

Liothyronine use in primary hypothyroidism — current concepts [PDF]

, 2021
Hypothyroidism is an endocrine disorder whose management raises many challenges in clinical practice. Its standard treatment is levothyroxine (LT4). The goal of the treatment is to normalize signs and symptoms, as well as to achieve thyroid-stimulating ...
Deutz Gómez-Condori, Diana Carolina; Division of Endocrinology, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Peru, Rivera-Fabián, Katia Eugenia; Division of Endocrinology, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Peru, Concepción-Zavaleta, Marcio José; Division of Endocrinology, Clínica Stella Maris, Lima, Peru, Ildefonso-Najarro, Sofía Pilar; Division of Endocrinology, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Peru, Valdivia Fernández-Dávila, Freddy Roynall; Division of Endocrinology, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Peru, Paz-Ibarra, José Luis; Division of Endocrinology, Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru, Herrera-Cabezas, Ramiro Grimaldo; Division of Internal Medicine, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Peru, Concepción-Urteaga, Luis Alberto; School of Medicine, Universidad Nacional de Trujillo, Peru   +7 more
core   +1 more source