Results 21 to 30 of about 2,262 (235)
Case Report: A homozygous selenocysteine insertion sequence-binding protein 2 (SECISBP2) gene mutation in a pediatric patient [PDF]
Selenocysteine insertion sequence-binding protein 2 (SECISBP2) is crucial for the biosynthesis of selenoproteins, including iodothyronine deiodinases, which play a vital role in thyroid hormone metabolism.
Lina Almohammadi +5 more
doaj +2 more sources
Role of T3 in Management of Hypothyroidism [PDF]
The management of hypothyroidism is based on the assumption that levothyroxine monotherapy normalizes thyroid hormone homeostasis, rendering patients clinically and biochemically euthyroid.
Sanjay Kalra +4 more
doaj +2 more sources
Objective To compare the effects of a unique fixed combination levothyroxine/liothyronine (LT4/LT3) therapy in patients with primary hypothyroidism. Subjects and methods This is a randomized, double-blind, crossover study.
Juliana Kaminski +4 more
doaj +2 more sources
Use of liothyronine (T3) in hypothyroidism: Joint British Thyroid Association/Society for endocrinology consensus statement [PDF]
\ua9 2023 The Authors. Clinical Endocrinology published by John Wiley & Sons Ltd.Persistent symptoms in patients treated for hypothyroidism are common.
Okosieme O +10 more
core +11 more sources
Background: Levothyroxine (LT4) monotherapy remains the standard treatment for hypothyroidism in current clinical practice. However, a subset of patients on LT4 continue to experience fatigue and other hypothyroid symptoms despite normal thyroid ...
Kal Peterman +3 more
doaj +2 more sources
Limiting the use and misuse of liothyronine in hypothyroidism
\ua9 Springer Nature Limited 2024. Liothyronine treatment for some patients with hypothyroidism has preoccupied academics, clinicians and patients for decades, and is a controversial topic in thyroidology.
Nagy EV, Hegedus L, Papini E, Perros P
core +6 more sources
ContextThe pharmacokinetics of liothyronine causes concerns for cardiovascular toxicity. While the effects of sustained increase in serum T3 concentrations are well described, little is known on the effects of acute changes in T3 concentrations due to ...
Shanshan Chen +9 more
doaj +1 more source
BackgroundThe standard treatment of hypothyroidism is levothyroxine (LT-4). However, there are several controversies regarding treatment of hypothyroid patients.AimTo investigate the Swedish endocrinologists’ use of thyroid hormones in hypothyroid and ...
Tereza Planck +8 more
doaj +1 more source
Liothyronine and levothyroxine prescribing in England: A comprehensive survey and evaluation [PDF]
Introduction The approach to thyroid hormone replacement varies across centres, but the extent and determinants of variation is unclear. We evaluated geographical variation in levothyroxine (LT4) and liothyronine (LT3) prescribing across General ...
Stedman, Mike +7 more
core +1 more source
INTRODUCTION: Over the past several years new evidence on the management of hypothyroidism has emerged, which has influenced recommendations from professional bodies.
Tomasz Bednarczuk +7 more
doaj +1 more source

