Results 21 to 30 of about 2,921 (250)

The Management of Thyroid Abnormalities in Chronic Heart Failure. [PDF]

, 2019
KEY POINTS Normal triiodothyronine (T3) levels are essential to preserve cardiac morphology and function. Overt and subclinical hypothyroidism are associated with an increased risk of heart failure, and levothyroxine is able to improve ...
Biondi, B
core   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Combination Thyroid Hormone Replacement; Knowns and Unknowns

Frontiers in Endocrinology, 2019
Hypothyroidism is common throughout the world and readily diagnosed with thyroid function tests. Management should be straightforward but appears not to be the case.
Peter N. Taylor, Vinay Eligar, Ilaria Muller, Anna Scholz, Colin Dayan, Onyebuchi Okosieme   +5 more
doaj   +1 more source

Hypothyroidism: The difficulty in attributing symptoms to their underlying cause

Frontiers in Endocrinology, 2023
Common symptoms of overt hypothyroidism are non-specific and include fatigue, lethargy, and dry skin. Although the diagnosis is considered to be straightforward, no single symptom can be used to identify patients with overt hypothyroidism, while many ...
Heleen I. Jansen, Heleen I. Jansen, Heleen I. Jansen, Anita Boelen, Anita Boelen, Anita Boelen, Annemieke C. Heijboer, Annemieke C. Heijboer, Annemieke C. Heijboer, Annemieke C. Heijboer, Eveline Bruinstroop, Eveline Bruinstroop, Eric Fliers, Eric Fliers   +13 more
doaj   +1 more source

In Vitro Assay Development and HTS of Small-Molecule Human ABAD/17β-HSD10 Inhibitors as Therapeutics in Alzheimer's Disease [PDF]

, 2017
This research was funded by the Scottish Universities Life Science Alliance (SULSA) assay development fund. This research was also kindly supported by The Rosetrees Trust and The Alzheimer’s Society, specifically The Barcopel Foundation, and partly ...
Andrew Pannifer, Angus Morrison, Frank J. Gunn-Moore, Gemma Baillie, Hughes M., Laura Aitken, Philip S. Jones, Stuart P. McElroy, Terry K. Smith   +8 more
core   +2 more sources

Unemployment and initiation of psychotropic medication:a case-crossover study of 2,348,552 Norwegian employees [PDF]

, 2016
Objectives: The study investigated initiation of psychotropic medication in relation to unemployment in the months before, during and after job loss to detect the period of greatest risk.Methods: The Norwegian working population in 2004 (N=2 348 552) was
Bjorngaard, Johan Hakon, Gunnell, David, Kaspersen, Silje, Ose, Solveig, Pape, Kristine   +4 more
core   +3 more sources

Antidepressant drugs and the response in the placebo group: the real problem lies in our understanding of the issue [PDF]

, 2012
In a recent paper, Horder and colleagues (Horder et al., 2010, J Psychopharmacol 25: 1277–1288) have suggested that the mainproblem in the Kirsch analysis is methodological. We argue that the results are similar irrespective of the method used.
Bech P, Fountoulakis KN, Hans-Jürgen Möller, Kirsch I, Kirsch I, Kirsch I, Konarski JZ, Konstantinos N Fountoulakis, Moncrieff J   +8 more
core   +1 more source

Effect of Liothyronine Treatment on Quality of Life in Female Hypothyroid Patients With Residual Symptoms on Levothyroxine Therapy: A Randomized Crossover Study

Frontiers in Endocrinology, 2022
ObjectiveThe effects of levothyroxine (LT4)/liothyronine (LT3) combination therapy on quality of life (QoL) in hypothyroid patients former on LT4 monotherapy have been disappointing.
Betty Ann Bjerkreim, Betty Ann Bjerkreim, Sara Salehi Hammerstad, Sara Salehi Hammerstad, Hanne Løvdal Gulseth, Tore Julsrud Berg, Tore Julsrud Berg, Lars Johan Omdal, Sindre Lee-Ødegård, Erik Fink Eriksen, Erik Fink Eriksen   +10 more
doaj   +1 more source

Trends in thyroid hormone prescribing and consumption in the UK [PDF]

, 2009
Background Thyroid hormone replacement is one of the most commonly prescribed and cost effective treatments for a chronic disease. There have been recent changes in community prescribing policies in many areas of the UK that have changed patient access ...
Anna L Mitchell, Bryan Hickey, Janis L Hickey, Simon HS Pearce, B Vaidya, GP Leese, GP Murray, CR Harington, R Bunevicius, S Grozinsky-Glasberg, RW Rees-Jones, R Braund, L Gatley, GM Hawksworth, ME Domino, NN Patel, The North Nottinghamshire prescribing strategy group, JL Hickey, KG White   +18 more
core   +1 more source

Type 3 Deiodinase and Consumptive Hypothyroidism: A Common Mechanism for a Rare Disease [PDF]

, 2013
The major product secreted by the thyroid is thyroxine (T4), whereas most of the biologically active triiodothyronine (T3) derives from the peripheral conversion of T4 into T3. The deiodinase enzymes are involved in activation and inactivation of thyroid
Cristina Luongo, Domenico Salvatore, Fausta Alfano, Luigi Trivisano   +3 more
core   +2 more sources