Results 11 to 20 of about 2,262 (235)

Changes in Thyroid Metabolites after Liothyronine Administration: A Secondary Analysis of Two Clinical Trials That Incorporated Pharmacokinetic Data

open access: yesMetabolites, 2022
We examined relationships between thyroid hormone (TH) metabolites in humans by measuring 3,5-diiodothyronine (3,5-T2) and 3-iodothyronamine (3-T1AM) levels after liothyronine administration.
Mark Danielsen   +2 more
exaly   +4 more sources

Combination therapy of liothyronine and levothyroxine for hypothyroidism-induced dilated cardiomyopathy [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism, 2022
Thyroid hormone plays a vital role in regulating human metabolism. They affect the functions of major organs, such as the brain, liver, skeletal muscle, and heart. Hypothyroidism can lead to dilated cardiomyopathy and decreased heart function.
Youngha Choi   +7 more
doaj   +3 more sources

Liothyronine for hypothyroidism: a candidate for disinvestment or in need of further research? A value of information analysis [PDF]

open access: yesBMJ Open, 2021
Objective Medicines with limited evidence of effectiveness are prime candidates for disinvestment. However, investment in further research may be preferable to deimplementation, given that the absence of evidence is not evidence of absence, and research ...
Dyfrig A Hughes   +3 more
doaj   +4 more sources

Nice guideline on thyroid disease: where does it take us with liothyronine? [PDF]

open access: yesThyroid Research, 2020
The new NICE guidelines on thyroid disease and its management do not recommend the routine use of liothyronine, but do not completely rule it out either.
Graham P. Leese
doaj   +2 more sources

Clinical Thyrotoxicosis Resulting from Liothyronine Augmentation of Antidepressant Therapy in an Adolescent

open access: yesCase Reports in Psychiatry, 2022
Background/Objective. Thyrotoxicosis, a condition resulting from excessive peripheral thyroid hormone, is typically accompanied by thyroid function tests demonstrating a high free thyroxine (free T4) with appropriate suppression of thyroid-stimulating ...
Benjamin A. Pallant   +2 more
doaj   +2 more sources

A 29-year-old Bodybuilder with Liothyronine-induced Thyrotoxic Hypokalaemic Periodic Paralysis [PDF]

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2021
We describe a 29-year-old male bodybuilder with recurrent attacks of myalgia and muscle weakness associated with hypokalaemia and thyrotoxicosis due to abuse of liothyronine.
Querijn van Bokhorst   +3 more
doaj   +2 more sources

Clinical Use and Perception About Synthetic Liothyronine for the Treatment of Primary Hypothyroidism Among Healthcare Professionals in India [PDF]

open access: yesIndian Journal of Endocrinology and Metabolism
Introduction: Hypothyroidism is commonly managed with levothyroxine (LT4) monotherapy, the standard treatment for many decades. However, 5%–10% of patients remain symptomatic despite achieving biochemical euthyroidism on LT4 monotherapy.
Sameer Aggarwal   +8 more
doaj   +2 more sources

Repositioning liothyronine for cancer immunotherapy by blocking the interaction of immune checkpoint TIGIT/PVR

open access: yesCell Communication and Signaling, 2020
Background Inhibitors targeting immune checkpoint were proved effective in cancer immunotherapy, such as PD-1/PD-L1 blockade. The novel immune checkpoint TIGIT/PVR plays critical roles in suppressing the anti-tumor effects of CD8+ T and NK cells, and ...
Xiuman Zhou   +12 more
doaj   +2 more sources

Quality by design driven RP-HPLC method optimization for analysis of levothyroxine and liothyronine in bulk and tablet dosage form [PDF]

open access: yesJournal of Applied Pharmaceutical Research
Background: Levothyroxine and Liothyronine are widely used in thyroid hormone replacement therapies. Simultaneously quantifying Levothyroxine and Liothyronine is important for managing thyroid hormone deficiency.
Ramdas Darade, Sanjay Pekamwar
doaj   +2 more sources

Effect of Liothyronine Treatment on Quality of Life in Female Hypothyroid Patients With Residual Symptoms on Levothyroxine Therapy: A Randomized Crossover Study

open access: yesFrontiers in Endocrinology, 2022
ObjectiveThe effects of levothyroxine (LT4)/liothyronine (LT3) combination therapy on quality of life (QoL) in hypothyroid patients former on LT4 monotherapy have been disappointing.
Hanne Løvdal Gulseth   +2 more
exaly   +3 more sources

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