Results 151 to 160 of about 42,940 (284)

Robustness of a convolutional neural network trained on dermoscopic images and challenged with close‐up images

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Deep learning‐convolutional neural networks (DL‐CNNs) have demonstrated high diagnostic accuracy within the domain of dermoscopy. However, many clinical settings lack dermoscopic devices, requiring reliance on close‐up images. This study evaluates the robustness of a DL‐CNN trained on dermoscopic images when challenged
Anastasia Sophie Vollmer   +6 more
wiley   +1 more source

Gastroenterological disorders and hepatic disease in adults with cerebral palsy: A systematic review

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To describe the incidence, prevalence, and prognostic factors for gastroenterological disorders and hepatic disease in adults with cerebral palsy (CP), and to examine the effectiveness of any screening or interventions. Method Six databases were searched for articles published in any language since 1990 meeting eligibility criteria ...
Christina M. Marciniak   +18 more
wiley   +1 more source

High‐density lipoproteins alleviate the endotoxin burden in patients with peritonitis and sepsis: The LIPS study

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Our data support the role for HDL and PLTP in the elimnation of LPS during human peritonitis with sepsis. Increased H4‐LPS elimination was associated with reduced inflammation and lower mortality. Abstract Background The high‐density lipoprotein (HDL) and the phospholipid transfer protein (PLTP) have been demonstrated to enhance endotoxin elimination ...
Maxime Nguyen   +11 more
wiley   +1 more source

pH-triggered liposomal strategy for cisplatin in lung cancer therapy. [PDF]

open access: yesSci Rep
Demirbolat GM   +5 more
europepmc   +1 more source

Feasibility and safety of awake craniotomy in adult patients with drug‐resistant focal epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Although awake craniotomy can guide functional brain mapping and resection, its feasibility and safety have been poorly studied in large series of patients with drug‐resistant focal epilepsy surgery. Methods We conducted an observational, retrospective, single‐center cohort study of 588 consecutive awake craniotomies (2010–2024 ...
Marc Zanello   +12 more
wiley   +1 more source

Overcoming BET‐inhibitor JQ1 resistance in aggressive non‐small cell lung cancer by inducing ferroptosis via inhibition of the BRD2–FTH1 axis

open access: yesThe FEBS Journal, EarlyView.
Recent studies emphasize alternative functions of FTH1 relevant for nuclear processes, such as transcriptional regulation. This study shows a novel FTH1/BRD2 association in non‐small cell lung carcinoma (NSCLC). This nuclear interaction affects BRD2 protein stability in aggressive NSCLC cells.
Stefania Scicchitano   +9 more
wiley   +1 more source

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