Results 151 to 160 of about 26,289 (283)

High‐density lipoproteins alleviate the endotoxin burden in patients with peritonitis and sepsis: The LIPS study

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Our data support the role for HDL and PLTP in the elimnation of LPS during human peritonitis with sepsis. Increased H4‐LPS elimination was associated with reduced inflammation and lower mortality. Abstract Background The high‐density lipoprotein (HDL) and the phospholipid transfer protein (PLTP) have been demonstrated to enhance endotoxin elimination ...
Maxime Nguyen   +11 more
wiley   +1 more source

Feasibility and safety of awake craniotomy in adult patients with drug‐resistant focal epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Although awake craniotomy can guide functional brain mapping and resection, its feasibility and safety have been poorly studied in large series of patients with drug‐resistant focal epilepsy surgery. Methods We conducted an observational, retrospective, single‐center cohort study of 588 consecutive awake craniotomies (2010–2024 ...
Marc Zanello   +12 more
wiley   +1 more source

Overcoming BET‐inhibitor JQ1 resistance in aggressive non‐small cell lung cancer by inducing ferroptosis via inhibition of the BRD2–FTH1 axis

open access: yesThe FEBS Journal, EarlyView.
Recent studies emphasize alternative functions of FTH1 relevant for nuclear processes, such as transcriptional regulation. This study shows a novel FTH1/BRD2 association in non‐small cell lung carcinoma (NSCLC). This nuclear interaction affects BRD2 protein stability in aggressive NSCLC cells.
Stefania Scicchitano   +9 more
wiley   +1 more source

Sex Differences in Health‐Related Quality of Life in Patients With Head and Neck Cancer—A Prospective Study

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Objective To analyse sex differences in health‐related quality of life (HRQL) before, during and up to 3 months posttreatment of head and neck cancer, and to examine the importance of salivary secretion rate for HRQL posttreatment. Methods Patients were recruited before starting curative oncologic treatment.
Niklas Bohm   +4 more
wiley   +1 more source

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