Results 21 to 30 of about 6,542 (163)
Frontiers in Oncology, 2023 BackgroundRenal clear cell carcinoma (RCC) has negative prognosis and high mortality due to its early diagnosis difficulty and early metastasis. Although previous studies have confirmed the negative progression of RCC is closely related to M2 macrophages
Xiaoxu Zhang +9 more
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The Physiological and Molecular Characterization of a Small Colony Variant of Escherichia coli and Its Phenotypic Rescue. [PDF]
PLoS ONE, 2016 Small colony variants (SCVs) can be defined as a naturally occurring sub-population of bacteria characterized by their reduced colony size and distinct biochemical properties.
Victor Santos, Irvin Hirshfield
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Pediatric Hematology Oncology Journal, 2023 Introduction: Wolman disease is a rare genetic disorder with an autosomal recessive inheritance. A mutation in the LIPA gene causes lysosomal acid lipase (LAL) deficiency results in lipid storage and adrenal insufficiency.
Indira Jayakumar +9 more
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PmrA/PmrB Two-Component System Regulation of lipA Expression in Pseudomonas aeruginosa PAO1
Frontiers in Microbiology, 2018 Pseudomonas lipases are well-studied, but few studies have examined the mechanisms of lipase expression regulation. As a global regulatory protein, PmrA controls the expression of multiple genes such as the Dot/Icm apparatus, eukaryotic-like proteins ...
Wu Liu +4 more
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A rare cause of hepatomegaly and dyslipidemia: lysosomal acid lipase deficiency
The Turkish Journal of Pediatrics, 2020 Background. Lysosomal acid lipase deficiency (LAL-D), also known as cholesteryl ester storage disease or Wolman disease, is a multi-systemic autosomal recessive genetic disorder caused by mutations in the lysosomal acid lipase gene (LIPA ...
Berrak Bilginer Gürbüz +3 more
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Molecular cloning of a light-inducible gene (lipA) encoding a novel pilin from Arthrobacter photogonimos [PDF]
FEMS Microbiology Letters, 1998 Development of pili on cells of Arthrobacter photogonimos is induced by photo-oxidative conditions. The nucleotide sequence was determined of a light-inducible gene (lipA) that encodes the precursor of a light-inducible pilin (designated LIP), a polypeptide of 212 amino acids.
H S, Yang, J K, Hoober
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BMC Biotechnology, 2012 Background Microbial lipases particularly Pseudomonas lipases are widely used for biotechnological applications. It is a meaningful work to design experiments to obtain high-level active lipase. There is a limiting factor for functional overexpression of
Wu Xiangping +5 more
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Genomic Organization of the Human Lysosomal Acid Lipase Gene (LIPA)
Genomics, 1994 Defects in the human lysosomal acid lipase gene are responsible for cholesteryl ester storage disease (CESD) and Wolman disease. Exon skipping as the cause for CESD has been demonstrated. We present here a summary of the exon structure of the entire human lysosomal acid lipase gene consisting of 10 exons, together with the sizes of genomic EcoRI and ...
C, Aslanidis +3 more
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Molecular Plant-Microbe Interactions, 2005 Xanthomonas oryzae pv. oryzae is the causal agent of bacterial leaf blight, a serious disease of rice. We demonstrated earlier that the type II secretion system (T2S) is important for virulence of X. oryzae pv. oryzae and that several proteins, including
R. Rajeshwari +2 more
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Journal of Biochemical and Clinical Genetics, 2019 Background: Wolman disease (WD) severe lysosomal acid lipase is a rare, autosomal recessive lysosomal storage disease caused by the absence or deficiency of lysosomal acid lipase enzyme. This deficiency leads to the accumulation of cholesterol esters and
Mansour J. Alwadani +4 more
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