Results 81 to 90 of about 74,383 (246)

Ion Pairing between Lipase and Colipase Plays a Critical Role in Catalysis [PDF]

, 1998
Laurence Ayvazian, Isabelle Crenon, J.A. Hermoso, David Pignol, Catherine Chapus, Brigitte Kerfélec   +5 more
openalex   +1 more source

Multimodal Chromatography in the Downstream Processing of mAb‐Based Products: Mechanisms, Strategies, and Applications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Multimodal chromatography has emerged as a powerful tool for the purification of monoclonal antibodies (mAbs) and their derivatives—including antibody fragments (Fabs), Fc‐fusions, bispecific (BsAb), and antibody–drug conjugates (ADCs)—offering enhanced selectivity through the integration of ionic, hydrophobic, hydrogen‐bonding, and π–π ...
Amin Javidanbardan, Marco P․ C․ Marques, Ana M. Azevedo, Daniel G. Bracewell, Stephen Goldrick   +4 more
wiley   +1 more source

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

Chronic Diseases and Translational Medicine, EarlyView.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy, Cornelius J. Fernandez, Mohammad Hamid Nedai, Joseph M. Pappachan   +3 more
wiley   +1 more source

Novel Hybrid Gel–Fiber Membranes as Carriers for Lipase Catalysis Based on Electrospinning and Gelation Technology

Gels
An excellent oil–water interface is one of the prerequisites for effective lipase catalysis. Therefore, this study aimed to improve lipase activity in terms of catalytic interface optimization.
Shumiao Lin, Qianqian Zhang, Ziheng Wang, Jinlong Li   +3 more
doaj   +1 more source

Gold Nanoparticles–Dynamic Constitutional Frameworks as Adaptive Hybrid Conjugates for Enzyme Immobilization

ChemistryEurope, EarlyView.
Dynamic constitutional frameworks (DCFs) and gold nanoparticles (AuNps) assemble into larger and well‐distributed conjugates providing an efficient platform for biosensing and biocatalytic applications. Dynamic constitutional frameworks (DCFs), connecting monomers via reversible covalent bonds, can initiate the assembly of gold nanoparticles (AuNps ...
Sanaa Daakour, Rosalinda Mazzei, Fabio Bazzarelli, Giuseppe Vitola, Lidietta Giorno, Mihail Barboiu   +5 more
wiley   +1 more source

More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations

Clinical Pharmacology &Therapeutics, EarlyView.
Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra, Viktoriia Starokozhko, Elisabeth Bakker, Anna Maria Gerdina Pasmooij, Peter Gerardus Maria Mol   +4 more
wiley   +1 more source

Withdrawal: Lipase maturation factor LMF1, membrane topology and interaction with lipase proteins in the endoplasmic reticulum. [PDF]

, 2019
Mark H. Doolittle, Saskia B. Neher, Osnat Ben-Zeev, Jo Ling-Liao, Ciara M Gallagher, Maryam Hosseini, Yin Fen, Howard Wong, Peter Walter, Miklós Péterfy   +9 more
openalex   +1 more source

Production of lipase by Bacillus altitudinis isolated from tannery effluent

, 2023
Nida Tanweer, Rimsha Dilshad, Rida Batool, Nazia Jamil   +3 more
openalex   +1 more source

Xylose Acetals ‐ a New Class of Sustainable Solvents and Their Application in Enzymatic Polycondensation

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
Novel organic solvents with an unmodified carbohydrate core were synthesised both from D‐xylose and directly from biomass and were successfully used as reaction media for lipase biocatalysts to synthesise aliphatic and aromatic polyesters. Abstract The use of organic solvents in academic research and industry applications is facing increasing ...
Anastasia O. Komarova, Cicely M. Warne, Hugo Pétremand, Laura König‐Mattern, Johannes Stöckelmaier, Chris Oostenbrink, Georg M. Guebitz, Jeremy Luterbacher, Alessandro Pellis   +8 more
wiley   +1 more source

Redox Biocatalysis in Lidocaine‐Based Hydrophobic Deep Eutectic Solvents: Non‐Conventional Media Outperform Aqueous Conditions

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
Two hydrophobic DESs, lidocaine/oleic acid and lidocaine/decanoic acid, were utilized as reaction media that were enzyme‐compatible and highly substrate‐solubilizer for carbonyl reduction catalyzed by horse liver alcohol dehydrogenase, focusing on the effect of water contents and on maximizing substrate loadings, which showcases for the first time the ...
Ningning Zhang, Viktoria Lahmann, Jan Philipp Bittner, Pablo Domínguez de María, Sven Jakobtorweihen, Irina Smirnova, Selin Kara   +6 more
wiley   +1 more source