Results 61 to 70 of about 43,319 (307)

Domain exchange: characterization of a chimeric lipase of hepatic lipase and lipoprotein lipase. [PDF]

Proceedings of the National Academy of Sciences, 1991
Hepatic lipase and lipoprotein lipase hydrolyze fatty acids from triacylglycerols and are critical in the metabolism of circulating lipoproteins. The two lipases are similar in size and amino acid sequence but are distinguished by functional differences in substrate preference and cofactor requirement.
H, Wong, R C, Davis, J, Nikazy, K E, Seebart, M C, Schotz   +4 more
openaire   +2 more sources

Produção e caracterização parcial de lipases com atividade de hidrólise e de síntese por fermentação em estado sólido de farelo de soja [PDF]

, 2009
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Alimentos, Florianópolis, 2009Este trabalho buscou isolar e selecionar novos microrganismos capazes de produzir lipases com ...
Rigo, Elisandra
core  

Epithelial SLC25A20 Deficiency Drives Immunosuppressive Neutrophil Remodeling via ARG1 Palmitoylation to Promote Colorectal Cancer

Advanced Science, EarlyView.
SLC25A20 deficiency in tumor cells compromises mitochondrial LCFA transport, which suppresses FAO and drives compensatory release of palmitic acid‐enriched lipids into the TME. These tumor‐derived palmitic acids are taken up by TANs, promoting ZDHHC18‐catalyzed ARG1 palmitoylation.
Yue Han, Tian‐Yuan Tan, Bin Zhang, Ye‐Bin Fu, Wen Chen, Min‐Hui Yang, Yi‐Qing Wang, Yan‐Qing Ding, Shuang Wang   +8 more
wiley   +1 more source

Production, Purification, and Characterization of Extracellular Lipases from Hyphopichia wangnamkhiaoensis and Yarrowia deformans

Fermentation
The efficient production of microbial lipases from organic wastes has garnered great interest because of the diverse and potential biotechnological applications of these enzymes. However, the extracellular lipases from the novel yeast strains Hyphopichia
Misael Romo-Silva, Emanuel Osmar Flores-Camargo, Griselda Ma. Chávez-Camarillo, Eliseo Cristiani-Urbina   +3 more
doaj   +1 more source

Síntese via enzimática de ésteres com lipases imobilizadas em filmes de dextrana [PDF]

, 2006
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Físicas e Matemáticas. Curso de Química.Lipases de diferentes fontes foram imobilizadas em filmes de dextranas e posteriormente utilizadas em reações de esterificação do ácido ...
FERRAZ , Alexandre Machado
core  

Advancing Biotherapeutic Treatment of Ulcerative Colitis Using Lipid Mesophases: Formulation Design and Preclinical Validation

Advanced Science, EarlyView.
Lipid mesophases provide a versatile platform for colon‐targeted delivery of biotherapeutics, protecting them from degradation while enhancing mucoadhesion and enabling localized, controlled release to the inflamed mucosa after oral or rectal administration. In a DSS‐induced colitis model, this strategy reduced disease activity, inflammatory biomarkers,
Rafaela Gazzi, Tiziana Cremona, Reto Czekalla, Emily Campbell, Marlene Schwarzfischer, Doris Pöhlmann, Vanessa Dobernig, Gerhard Rogler, Michael Scharl, Alessandra Bergadano, Raffaele Mezzenga, Martin Kuentz, Paola Luciani, Simone Aleandri   +13 more
wiley   +1 more source

Harnessing Waste Bread: From Potential Use in Microbial Growth and Enzyme Production to Techno-Economic Assessment

Microorganisms
This study highlights waste bread (WB) as a novel, cost-effective, and nutrient-rich substrate for microbial growth, offering a sustainable alternative to conventional media.
Sameh Ben Mabrouk, Bouthaina Ben Hadj Hmida, Wejdene Sallami, Salma Dhaouadi, Theodoros Varzakas, Slim Smaoui   +5 more
doaj   +1 more source

Analysis of Bacterial Isolates Capable of Partially Degrading Polyethylene Terephthalate [PDF]

Brazilian Archives of Biology and Technology
In this work, we studied 46 bacterial isolates to determine their potential for polyethylene terephthalate (PET) degradation. Only eight lipase-positive isolates were pre-selected to continue analysis.
Ana Sofía Fierros-Peña, Maribel Mireles-Martínez, Jorge Alberto Torres-Ortega, Marco Antonio Garza-Navarro, Jesús Manuel Villegas-Mendoza, Ninfa María Rosas-García   +5 more
doaj   +1 more source

Caracterização bioquímica de duas lipases mutantes de Staphylococcus xylosus e de uma esterase de Lactobacillus plantarum imobilizada em polipropileno [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Ciência dos Alimentos, Florianópolis, 2010As lipases e esterases pertencem ao grupo das hidrolases e são enzimas capazes de ...
Kolling, Deise Juliana
core  

VCP‐Regulated LMF2 Stabilizes the Cholesterol Biosynthesis Enzyme HMGCS1 to Drive Cancer Progression and Confer Capecitabine Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
LMF2 drives progression and capecitabine resistance in triple‐negative breast cancer (TNBC). Mechanistically, VCP prevents NBR1‐mediated autophagic degradation of LMF2, thereby stabilizing it. Stabilized LMF2 subsequently suppresses NDP52‐mediated autophagic degradation of HMGCS1, a rate‐limiting cholesterol biosynthesis enzyme.
Qian Zhao, Lisa Andriani, Yin‐Ling Zhang, Shao‐Ying Yang, Yun‐Xiao Ling, Min‐Ying Huang, Jia‐Yang Cai, Fang‐Lin Zhang, Xin Hu, A‐Yong Cao, Zhi‐Min Shao, Guang‐Yu Liu, Da‐Qiang Li   +12 more
wiley   +1 more source