Results 51 to 60 of about 43,319 (307)

Single‐Nucleus Atlas of Spinal Sarcopenia Patients Reveals Disruption of Quiescent and Regenerative Satellite Cell Niches in Fatty‐Infiltrated Muscle

open access: yesAdvanced Science, EarlyView.
Mechanisms of Fatty Infiltration and Muscle Degeneration. Clinical metadata identified intramuscular fat accumulation as an independent driver of muscle mass decline. Single‐nucleus RNA sequencing of spinal sarcopenia muscle revealed adipogenic reprogramming of fibro‐adipogenic progenitors, satellite‐cell niche disruption, and elevated levels of the ...
Wenkai Wu   +18 more
wiley   +1 more source

Prediction of lipase-specific foldase-dependence in bacterial lipase subfamilies I.1 and I.2

open access: yesBMC Genomics
Background Most bacterial lipases in subfamily I.1/I.2 depend on a specific chaperone protein, lipase-specific foldase (Lif), for folding into their active form. In contrast, several Lif-independent lipases have been reported in subfamily I.1.
Takahiro Hioki
doaj   +1 more source

Nanopartículas de poli-hidroxibutirato-co-valerato como suporte para a imobilização da lipase de Candida antarctica fração B

open access: yesQuímica Nova, 2014
This work evaluates the immobilization of Candida antarctica lipase (Fraction B) using poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) nanoparticles as support.
Ilizandra A. Fernandes   +7 more
doaj   +1 more source

Estudos de reações de transesterificação com lipases imobilizadas e determinação de coeficiente de difusão de ésteres em organo-gel / [PDF]

open access: yes, 1999
Tese (Doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas.As lipases de Chromobacterium viscosum, Pseudomonas sp, Microbial e Lipolase, imobilizadas em organo-gel (MBG) de hexano foram usadas como ...
João, Jair Juarez
core  

A Robust Bio‐Supportive Hydrogel Patch for Full‐Thickness Repair of Gastroesophageal Defects

open access: yesAdvanced Science, EarlyView.
Gastroesophageal defect repair remains a formidable clinical challenge plagued by high leakage and life‐threatening complications. We develop a double‐disc, highly crystalline PVA‐based RBS hydrogel patch featuring suture‐free sealing, robust acid/enzyme resistance and mechanical durability.
Xingqi Song   +13 more
wiley   +1 more source

Progress on the Classification, Characteristics and Food Industry Application of Microbial Proteases and Lipases

open access: yesShipin gongye ke-ji
Proteases and lipases are two major kinds of industrial hydrolysis enzymes and widely used in various food industry (e.g., cheese making, soy sauce fermentation, liquor brewing, meat tenderization, etc.).
Yao ZHANG   +5 more
doaj   +1 more source

Reações de acilação enantiosseletiva de aminas e álcool alifáticos catalisadas por lipases [PDF]

open access: yes, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2015.Neste trabalho, as lipases comerciais LSD, LAY, LAK, LM, LCR, e as nativas de A.
Silva, Julyetty Crystyne da
core  

Production of Lipases by Certain Thermo Tolerant Bacteria

open access: yes, 2017
Lipases are hydrolytic enzymes which hydrolyse triglycerides to free fatty acids and glycerol. Bacterial lipase producers were isolated from certain loamy arid soils.
Ghaidaa Mohammed   +1 more
core   +1 more source

Yoda1‐Functionalized Nanozymes Coordinate Piezo1 Activation and Mitochondrial Protection to Reprogram the Diabetic Osteoimmune Micromilieu and Promote Vascularized Bone Repair

open access: yesAdvanced Science, EarlyView.
Diabetic bone defects remain a critical clinical challenge. A 3D‐printed BCPG‐MF@Y scaffold, embedding Yoda1‐functionalized manganese dioxide‐ferritin nanozymes, scavenges mtROS, suppresses the cGAS–STING pathway, and reverses cellular senescence, while Yoda1 activates Piezo1 to direct BMSCs fate to synergistically reprogram the osteoimmune ...
Qing‐Song Deng   +16 more
wiley   +1 more source

Chlorination‐Driven BODIPY Fluorescent Probes for the Selective Monitoring of Myeloperoxidase Activity in Cells and Inflamed Mouse Models

open access: yesAngewandte Chemie, EarlyView.
A meso‐carboxamide‐substituted BODIPY fluorescent probe reports myeloperoxidase (MPO) activity via electrophilic chlorination by MPO‐derived HOCl, generating a highly emissive chlorinated product with a ca. 40 nm bathochromic shift. Applications in quantitative MPO assays, cellular imaging of MPO‐derived HOCl, redox‐dependent discrimination of cancer ...
Siyoung Cho   +3 more
wiley   +2 more sources

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