Results 101 to 110 of about 114,843,840 (203)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

CtBP1-S/BARS regulates Lipid Droplets biogenesis

, 2016
Lipid droplets (LDs) are intracellular lipid-storing organelles surrounded by a phospholipid monolayer. LDs emerge as metabolically active organelles involved in many biological processes and linked to the pathogenesis of several dysfunctions including ...
Valente C, Circolo D, Ikonen E, Luini A, Corda D, Filograna A   +5 more
core  

Uric Acid Extremes and Lipid Dysregulation: Evidence from a Large Population-Based Study

Background: Uric acid (UA) exhibits a dual role, with anti-oxidant or pro-oxidant effects determined by its concentration. However, its association with lipid metabolism across different uric acid states remains unclear.
Ahmed M. Basudan, Mohammad A. Alfhili, Yazeed Alshuweishi, Zeina S. Alkudmani   +3 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The Determination Of Salinity Profile And Nutrition (Nah2po4) Profile In Utilizing Nannochloropsis oculata To Gain Maximum Lipid [PDF]

, 2012
The determination of salinity profile and nutrition (NaH2PO4) profile in utilizing Nannochloropsis oculata to gain maximum lipid was investigated. The purpose of carrying out this research is to determine the optimum salinity and the optimum nutrition ...
Elida , Purba,, Kenjiro , Siburian
core   +1 more source

High level of individual lipid profile and lipid ratio as a predictive marker of poor glycemic control in type-2 diabetes mellitus

Vascular Health and Risk Management, 2019
I Made Junior Rina Artha,1 Agha Bhargah,1,2 Nyoman Khrisna Dharmawan,2 Utami Wijayaswari Pande,2 Komang Agus Triyana,2 Pande Agung Mahariski,2 Jessica Yuwono,2 Varennia Bhargah,2 I Putu Yuda Prabawa,3 Ida Bagus Amertha Putra Manuaba,4,5 I Ketut ...
Artha IMJR, Bhargah A, Dharmawan NK, Pande UW, Triyana KA, Mahariski PA, Yuwono J, Bhargah V, Prabawa IPY, Manuaba IBAP, Rina IK   +10 more
doaj  

Is a Single Lipoprotein(a) Measurement Once in a Lifetime Sufficient? The Results from the STAR-Lp(a) Study

Medical Sciences
Background: Guidelines suggest that a single lifetime measurement of lipoproteina(a) [Lp(a)] is sufficient for most patients as its levels are largely genetically determined and do not significantly change over time.
Monika Burzyńska, Piotr Jankowski, Maciej Banach, Michał Chudzik   +3 more
doaj   +1 more source