Results 101 to 110 of about 1,789,531 (316)

Lipid Sorting: Lipids Do It on Their Own [PDF]

open access: yesCurrent Biology, 2005
How are lipid molecules sorted between organelles in eukaryotic cells? A recent paper shows that the work needed to bend a membrane and form a vesicle is sufficient to sort lipid molecules.
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Interplay of Klebsiella pneumoniae fabZ and lpxC Mutations Leads to LpxC Inhibitor-Dependent Growth Resulting from Loss of Membrane Homeostasis

open access: yesmSphere, 2018
Tight coordination of inner and outer membrane biosynthesis is very important in Gram-negative bacteria. Biosynthesis of the lipid A moiety of lipopolysaccharide, which comprises the outer leaflet of the outer membrane has garnered interest for Gram ...
Mina Mostafavi   +10 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Synthesis of resorcinolic lipids bearing structural similarities to cytosporone A

open access: yesQuímica Nova, 2009
Inspired by the structure and biological activities of resorcinolic lipids and, particularly cytosporone A- a potent inhibitor of plantule germination and growth, we have performed the synthesis of the analogs 3-heptyl-3-hydroxy-5,7-dimethoxy-2 ...
Edson dos Anjos dos Santos   +4 more
doaj   +1 more source

Lipid composition of gluten-free wafer snack present in the Italian market

open access: yes, 2015
Celiac disease, a pathology related to intolerance at gliadin fraction of wheat and the prolamin that leads to small intestine inflammation with malabsorption of some nutrients (such as folic acid, calcium, iron and fat-soluble vitamins), has widely ...
CARDENIA, VLADIMIRO   +2 more
core  

Chapter 2 Lipid Environmental Modulation of Activity of Photosynthetic Membrane Proteins

open access: yes, 2008
Lipid Environmental Modulation of Activity of Photosynthetic Membrane ...
Trotta, M.   +9 more
core   +1 more source

Designer lipid-like peptides [PDF]

open access: yes, 2011
A crucial bottleneck in membrane protein studies, particularly G-protein coupled receptors, is the notorious difficulty of finding an optimal detergent that can solubilize them and maintain their stability and function. Here we report rapid production of
Braun, Dieter   +11 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Biochemical Characterization for Lipid Synthesis in Aspergillus niger

open access: yesمجلة بغداد للعلوم, 2016
A niger, a fungus which doesn't have high ability to production lipid, this fungus has been select to investigate the non oleaginicity. In this search, there are explorations about: i) growth profile ii) enzymes profile iii) isoforms.
Baghdad Science Journal
doaj   +1 more source

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