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The role of FATP1 in lipid accumulation: a review
Molecular and Cellular Biochemistry, 2021Lipid accumulation in mammals has been widely studied for decades due to its significant association with obesity in humans and meat quality in livestock animals. Fatty acid transport 1 (FATP1) is an evolutionarily conserved protein that localizes to the plasma membrane to enhance the transportation of fatty acids (FAs).
Jieping Huang, Ruirui Zhu, Deshun Shi
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Lipids easy to accumulate in the liver and lipids hard to accumulate in it
Nutrition Research, 1997Abstract Accumulation of lipids in the liver, fatty acid composition and molecular species of serum and hepatic triglycerides were investigated after rats were raised for 4 weeks with diets containing beef powder and 12% level of various lipids. Some diagnostic parameters in the serum and acetyl-CoA carboxylase and peroxisomal β-oxidation activities ...
Satoshi Kawahara +4 more
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Lipid Accumulation in Dysferlin-Deficient Muscles
The American Journal of Pathology, 2014Dysferlin is a membrane associated protein involved in vesicle trafficking and fusion. Defects in dysferlin result in limb-girdle muscular dystrophy type 2B and Miyoshi myopathy in humans and myopathy in A/J(dys-/-) and BLAJ mice, but the pathomechanism of the myopathy is not understood.
Grounds, M. +6 more
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Controlling lipid accumulation in cereal grains
Plant Science, 2012Plant oils have so far been mostly directed toward food and feed production. Nowadays however, these oils are more and more used as competitive alternatives to mineral hydrocarbon-based products. This increasing demand for vegetable oils has led to a renewed interest in elucidating the metabolism of storage lipids and its regulation in various plant ...
Barthole, Guillaume +3 more
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Accumulation of lipids and lipid-intermediates in the heart during ischaemia
1987The content of non-esterified fatty acids (NEFA) and their CoA and carnitine esters is low in normoxic cardiac tissue. The majority of fatty acids is esterified in the triacylglycerol and phosphoglyceride pool. During myocardial ischaemia beta-oxidation of fatty acids is inhibited. In addition, turnover of the esterified fatty acid pools is most likely
G J, van der Vusse +4 more
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Lipid Accumulation Mechanisms in Auto- and Heterotrophic Microalgae
Journal of Agricultural and Food Chemistry, 2017Microalgae lipids have attracted great attention in the world as a result of their potential use for biodiesel productions. Microalgae are cultivated in photoautotrophic conditions in most cases, but several species are able to grow under heterotrophic conditions, in which microalgae are cultivated in the dark where the cell growth and reproduction are
Hao-Hong Chen, Jian-Guo Jiang
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Regulation of lipid accumulation in oleaginous microorganisms
Biochemical Society Transactions, 2002A small number of eukaryotic micro-organisms, the oleaginous species, can accumulate triacylglycerols as cellular storage lipids, sometimes up to 70% of the biomass. Some of these lipids, particularly those containing high proportions of polyunsaturated fatty acids of nutritional and dietary importance, are now in commercial production; these are known
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Accumulation of lipid and nonlipid constituents in rabbit atheroma
Journal of Atherosclerosis Research, 1964Summary Six groups of 10 rabbits each were fed 1% cholesterol for periods up to 4 months. Free and esterified cholesterol of the thoracic intima were observed to increase exponentially early in the experiment. The rate of cholesterol accumulation was found to depend on time of exposure to atherogenic diet as well as on serum cholesterol level.
H A, NEWMAN, D B, ZILVERSMIT
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Oxfenicine-induced accumulation of lipid in the rat myocardium
Journal of Molecular and Cellular Cardiology, 1988Oxfenicine inhibits myocardial metabolism of nonesterified fatty acids (NEFA). The purpose of the present study was to examine the effects of oxfenicine on triglyceride accumulation and the development of histologically visible lipid droplets. The beta-agonist isoproterenol was used to induce elevated arterial NEFA. Four groups of rats were used in the
H, Jodalen +4 more
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Perivascular accumulation of lipids in the infant human brain
Acta Neuropathologica, 1971The accumulation of sudanophilic material in and around small telencephalic vessels was studied in 215 randomly collected brains of infants and children up to 8 years in relation to age and the primary lethal disease process. Before the fourth postnatal week lipid deposits occur in the premyelination glia and in endothelial and perithelial cells. After
K, Jellinger, F, Seitelberger, M, Kozik
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