Results 121 to 130 of about 779,547 (295)
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian +7 more
wiley +1 more source
Electrodynamic droplet actuation for lab on a chip system
This work presents the development of electrowetting on dielectric and liquid dielectrophoresis as a platform for chemistry, biochemistry and biophysics.
Aghdaei, Sara
core +1 more source
Lipid bilayers represent the interface between the cell and its environment, serving as model systems for the study of various biological processes. For instance, the addition of small molecules such as alcohols is a well-known process that modulates ...
Shova Neupane +3 more
doaj +1 more source
PEG‐guided mitochondrial surface engineering supports structural stabilization and controlled presentation of cell‐penetrating peptides. CPP–PEG‐modified mitochondria exhibit enhanced cellular uptake and uptake‐associated respiratory modulation, providing a proof‐of‐concept framework for modular organelle engineering and future bioenergetic modulation ...
Masahiro Shiraishi +9 more
wiley +1 more source
Structural and Dynamic Properties of Lipid‐Coated Gold Nanoparticles
Atomistic molecular dynamics simulations reveal how lipid chemistry governs the behavior of coatings on the surface of a gold nanoparticle. Variations in headgroup charge and acyl‐chain saturation produce distinct monolayer‐like lipid organization, ranging from compact, ordered coatings to extended, dynamic shells. These findings establish a foundation
Kalpani A. Mirihana +4 more
wiley +1 more source
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le +4 more
wiley +1 more source
Amphiphilic, monolayer-protected gold nanoparticles (NPs) have been shown to enter cells via a non-endocytic, non-disruptive pathway that could be valuable for biomedical applications.
Reid C Van Lehn, Alfredo Alexander-Katz
doaj +1 more source
An understanding of the cellular uptake and trafficking of nanoparticles is important for the design of efficient nanoparticle-based nanomedicines. Herein we compare the uptake and cytotoxicity of diamond-shape, lanthanide upconverting nanoparticles ...
John A. Capobianco +9 more
core +1 more source
A label‐free impedimetric biosensor based on electroactive 3D porous graphene foam enables ultrasensitive and selective detection of CD81 protein and MCF‐7 cell‐derived extracellular vesicles in human serum. Detection limits of 0.048 fg/mL for CD81 and ∼24 EVs/mL are achieved, demonstrating a robust platform for selective, label‐free, and ...
Michael Robert Furness +11 more
wiley +1 more source
3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi +4 more
wiley +1 more source

