Results 101 to 110 of about 112,656 (211)

Lipid Saturation and Cholesterol Drive the Mechanical Response of Lipid Bilayer to Ionic Liquid: An Atomic Force Microscopy Study. [PDF]

Langmuir
Yedelkina A, Rodriguez BJ, Podestà A, Benedetto A.   +3 more
europepmc   +1 more source

Super-swelling behavior of stacked lipid bilayer systems. [PDF]

Eur Phys J E Soft Matter, 2023
Rueben J, Steer D, Leal C.
europepmc   +1 more source

Hemoglobin's α‐Helix‐to‐β‐Sheet Transition Enables Targeted mRNA Delivery to the Lung

Advanced Science, EarlyView.
Acidic heating converts hemoglobin into β‐sheet‐rich fibrils with positively charged surfaces. These hemoglobin fibrils electrostatically complex IL‐11 scFv mRNA, selectively bind circulating platelets, and hitchhike to the lung, where they are enriched in fibroblasts.
Xihua Liu, Saiya Li, Guodong Wu, Shuangjian Li, Long Shuang Huang, Xiaoyang Li, Yiguo Zhao, Wei Lu, Cuixia Sun, Qin Cao, Yapeng Fang, Yiping Cao   +11 more
wiley   +1 more source

Structure and composition of supported lipid bilayers: a comparison between solvent-assisted lipid bilayer and vesicle fusion methods. [PDF]

J Appl Crystallogr
Felderer B, Buchanan C, Wang S, Shen HH, Nelson A, Hall SCL, Cárdenas M.   +6 more
europepmc   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

The lipid bilayer strengthens the cooperative network of membrane proteins. [PDF]

Sci Adv
MuhammedNazaar S, Yao J, Necelis MR, Park YC, Shen Z, Bridges MD, Guo R, Swope N, Rhee MS, Kim M, Kim KH, Hubbell WL, Fleming KG, Columbus L, Kang SG, Hong H.   +15 more
europepmc   +1 more source

Identification of a Nonribosomal Peptide Analog With Activity Against Multiple Gram‐Positive Bacteria via a Synthetic Bioinformatic Natural Product Discovery Approach

Advanced Science, EarlyView.
The genome of Rhodococcus erythropolis D‐1 was analyzed by bioinformatic tools to mine a novel nonribosomal peptide synthetase (NRPS) gene cluster. A nonribosomal peptide analog ZURJC5 associated with the NRPS was chemically synthesized. Through structure‐activity relationship studies, ZURJC28 was ultimately obtained and showed antibacterial activity ...
Keyi Chen, Jiayi Liang, Yujia Wu, Jianan Xu, Yi Liu, Wenguang Wang, Xinhang Jiang, Benjie Gao, Yueyue Wang, Hui Jiang   +9 more
wiley   +1 more source

Allosteric coupling between a lipid bilayer and a membrane protein. [PDF]

Biophys J
Fourel C, Gautier Y, Pozza A, Giraud F, Point E, Le Bon C, Moncoq K, Stirnemann G, Hénin J, Lescop E, Catoire LJ.   +10 more
europepmc   +1 more source

TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain

Advanced Science, EarlyView.
TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando, Emanuele Buratti, Francesca Paron   +2 more
wiley   +1 more source

Aquaporin embedded suspended lipid bilayer on anodized alumina nanoporous substrates for studying stability and functionality: towards the development of a miniaturized water purifier. [PDF]

Nanoscale Adv
Kumari A, Bhattacharya J, Ghosh Moulick R.   +2 more
europepmc   +1 more source