Results 71 to 80 of about 779,547 (295)
Triglyceride blisters in lipid bilayers: implications for lipid droplet biogenesis and the mobile lipid signal in cancer cell membranes. [PDF]
PLoS ONE, 2010 Triglycerides have a limited solubility, around 3%, in phosphatidylcholine lipid bilayers. Using millisecond-scale course grained molecular dynamics simulations, we show that the model lipid bilayer can accommodate a higher concentration of triolein (TO)
Himanshu Khandelia +3 more
doaj +1 more source
Membranes, 2022 Functional biointerfaces hold broad significance for designing cell-responsive medical implants and sensor devices. Solid-supported phospholipid bilayers are a promising class of biological materials to build bioinspired thin-film coatings, as they can ...
Sigalit Meker +7 more
doaj +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Membrane-Accelerated Amyloid-β Aggregation and Formation of Cross-β Sheets
Membranes, 2017 Amyloid- β aggregates play a causative role in Alzheimer’s disease. These aggregates are a product of the physical environment provided by the basic neuronal membrane, composed of a lipid bilayer.
Adree Khondker +2 more
doaj +1 more source
A Lipid-Bilayer-On-A-Cup Device for Pumpless Sample Exchange
Micromachines, 2020 Lipid-bilayer devices have been studied for on-site sensors in the fields of diagnosis, food and environmental monitoring, and safety/security inspection.
Yoshihisa Ito +8 more
doaj +1 more source
Micromachines, 2023 The plasma membrane is a lipid bilayer that establishes the outer boundary of a living cell. The composition of the lipid bilayer influences the membrane’s biophysical properties, including fluidity, thickness, permeability, phase behavior, charge ...
Shide Bakhtiari +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Effects of carotenoids on lipid bilayers
Physical Chemistry Chemical Physics, 2018 Carotenoids have been found to be important in improving the integrity of biomembranes in eukaryotes.
Quentin R. Johnson +4 more
openaire +3 more sources
Transmembrane helix dynamics of bacterial chemoreceptors supports a piston model of signalling. [PDF]
, 2011 Transmembrane α-helices play a key role in many receptors, transmitting a signal from one side to the other of the lipid bilayer membrane. Bacterial chemoreceptors are one of the best studied such systems, with a wealth of biophysical and mutational data
Judith P Armitage +12 more
core +1 more source