Results 71 to 80 of about 140,194 (304)

Comparative computational study of interaction of C60-fullerene and tris-malonyl-C60-fullerene isomers with lipid bilayer: relation to their antioxidant effect. [PDF]

PLoS ONE, 2014
Oxidative stress induced by excessive production of reactive oxygen species (ROS) has been implicated in the etiology of many human diseases. It has been reported that fullerenes and some of their derivatives-carboxyfullerenes-exhibits a strong free ...
Marine E Bozdaganyan, Philipp S Orekhov, Alexey K Shaytan, Konstantin V Shaitan   +3 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

A Comparative Study of Phase States of the Peribacteroid Membrane from Yellow Lupin and Broad Bean Nodules

Biochemistry Research International, 2014
A comparative study of the lipid bilayer phase status and structure of the outer membrane of free-living Bradyrhizobium strain 359a (Nod+Fix+) and 400 (Nod+FixL) or Rhizobium leguminosarum 97 (Nod+Fix+, effective) and 87 (Nod+FixL, ineffective) has been ...
Natalia N. Kudryavtseva, Alexis V. Sof’in, Georgiy S. Bobylev, Evgeny M. Sorokin   +3 more
doaj   +1 more source

FLUCTUATIONS IN LIPID BILAYERS: ARE THEY UNDERSTOOD? [PDF]

Biophysical Reviews and Letters, 2013
We review recent computer simulation studies of undulating lipid bilayers. Theoretical interpretations of such fluctuating membranes are most commonly based on generalized Helfrich-type elastic models, with additional contributions of local "protrusions" and/or density fluctuations. Such models provide an excellent basis for describing the fluctuations
openaire   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Transmembrane helix dynamics of bacterial chemoreceptors supports a piston model of signalling. [PDF]

, 2011
Transmembrane α-helices play a key role in many receptors, transmitting a signal from one side to the other of the lipid bilayer membrane. Bacterial chemoreceptors are one of the best studied such systems, with a wealth of biophysical and mutational data
Judith P Armitage, Judith P. Armitage, Sansom, MS, Armitage Judith P., Mark S P Sansom, Armitage, JP, Benjamin A Hall, Sansom Mark S. P., Hall, BA, Armitage, Judith, Benjamin A. Hall, Mark S. P. Sansom, Hall Benjamin A.   +12 more
core   +2 more sources

Liposomal lipid nanoparticles for extrahepatic delivery of mRNA

Nature Communications
Long-circulating, transfection-competent lipid nanoparticle (LNP)-mRNA delivery systems are critical for achieving efficient transfection in extrahepatic tissues.
Miffy Hok Yan Cheng, Yao Zhang, Kevin Fox, Jerry Leung, Colton Strong, Emma Kang, Yihang Chen, Michelle Tong, Hemashree Bommadevara, Eric Jan, Owen Yuk Long Ip, Cristina Rodríguez-Rodríguez, Katayoun Saatchi, Urs O. Häfeli, Amir Abdolahzadeh, Dominik Witzigmann, Pieter R. Cullis   +16 more
doaj   +1 more source

Triglyceride blisters in lipid bilayers: implications for lipid droplet biogenesis and the mobile lipid signal in cancer cell membranes. [PDF]

PLoS ONE, 2010
Triglycerides have a limited solubility, around 3%, in phosphatidylcholine lipid bilayers. Using millisecond-scale course grained molecular dynamics simulations, we show that the model lipid bilayer can accommodate a higher concentration of triolein (TO)
Himanshu Khandelia, Lars Duelund, Kirsi I Pakkanen, John H Ipsen   +3 more
doaj   +1 more source

Inkjet-Printed Phospholipid Bilayers on Titanium Oxide Surfaces: Towards Functional Membrane Biointerfaces

Membranes, 2022
Functional biointerfaces hold broad significance for designing cell-responsive medical implants and sensor devices. Solid-supported phospholipid bilayers are a promising class of biological materials to build bioinspired thin-film coatings, as they can ...
Sigalit Meker, Oded Halevi, Hokyun Chin, Tun Naw Sut, Joshua A. Jackman, Ee-Lin Tan, Michael G. Potroz, Nam-Joon Cho   +7 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source