Results 111 to 120 of about 511,973 (318)

Lipidomic Profiling of the Epidermis in a Mouse Model of Dermatitis Reveals Sexual Dimorphism and Changes in Lipid Composition before the Onset of Clinical Disease.

, 2020
Atopic dermatitis (AD) is a multifactorial disease associated with alterations in lipid composition and organization in the epidermis. Multiple variants of AD exist with different outcomes in response to therapies.
Franco, Jackeline, Rajwa, Bartek, John P. Sundberg, Bartek Rajwa, Christina R. Ferreira, HogenEsch, Harm, Ferreira, Christina R, Sundberg, John P, Harm HogenEsch, Jackeline Franco   +9 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Differentiation of histological calcification classifications in breast cancer using ultrashort echo time and chemical shift-encoded imaging MRI

Frontiers in Oncology
IntroductionDuctal carcinoma in situ (DCIS) accounts for 25% of newly diagnosed breast cancer cases with only 14%–53% developing into invasive ductal carcinoma (IDC), but currently overtreated due to inadequate accuracy of mammography.
Yazan Ayoub, Sai Man Cheung, Boddor Maglan, Nicholas Senn, Kwok-Shing Chan, Kwok-Shing Chan, Jiabao He   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Processing effects on lipid composition in ultra-processed foods: assessing health assumptions and association with blood lipid profiles

Cogent Food & Agriculture
This study investigated the effects of various processing methods on the lipid composition of ultra-processed foods (UPFs), specifically focusing on high-temperature frying, hydrogenation, freezing, and thawing.
Putri Widyanti Harlina, Vevi Maritha, Fang Geng, Asad Nawaz, Edy Subroto, Bangkit Wiguna, Endah Wulandari, Fetriyuna Fetriyuna   +7 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Lipid Characterization of Beach-Cast Seaweeds from Gran Canaria Island: Potential Use in Human and Animal Nutrition

Journal of Marine Science and Engineering
Macroalgal wracks can be considered unpleasant for beach users and, consequently, they are usually collected from most touristic beaches and discarded.
Ana Galindo, Coraima del Mar García, José Antonio Pérez, Beatriz Abdul-Jalbar, Marianna Venuleo, Nieves Guadalupe Acosta, Manuel Marrero, Covadonga Rodríguez   +7 more
doaj   +1 more source

Lipid Composition of Mayonnaise

The Japanese Journal of Nutrition and Dietetics, 1970
It is advisable to use vegetable oil in fat-controled diet, because it contains poly-enoic fatty acids.Mayonnaise is an oil-vinegar emulsion made from vinegar and vegetable oil stabilized with egg-yolk.We analysed lipid composition of eight brands of mayonnaise.The ratio of poly-unsaturated fatty acids to saturated fatty acids approximates two or three
Ono, Fusako, Sugiyama, Noriko, Sato, Fumiyo, Fukushima, Haruko, Machii, Yoko   +4 more
openaire   +2 more sources

Study of protein-bacteriochlorophyll and protein-lipid interactions of natural and model light-harvesting complex 2 in purple bacterium Rhodobacter sphaeroides. [PDF]

, 2007
The natural design of the photosystems of plants and photosynthetic bacteria using chlorophylls (Chls) or bacteriochlorophylls (BChls) as photoreceptors are robust.
Kwa, Lee Gyan
core