Results 211 to 220 of about 4,092,639 (351)

Identification of essential sites of lipid peroxidation in ferroptosis

Nature Chemical Biology, 2023
A. N. von Krusenstiern, R. Robson, Naixin Qian, Baiyu Qiu, Fanghao Hu, Eduard Reznik, N. Smith, Fereshteh Zandkarimi, Verna M. Estes, Marcel M. Dupont, Tal Hirschhorn, M. Shchepinov, Wei Min, K. Woerpel, B. Stockwell   +14 more
semanticscholar   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

Phytyl Phenolipids: Structurally Modified Antioxidants with Superior Lipid Membrane Interaction. [PDF]

Molecules
Costa V, Costa M, Rebelo R, Arques F, Ferreira M, Gameiro P, Barros T, Geraldo D, Monteiro LS, Paiva-Martins F.   +9 more
europepmc   +1 more source

Unraveling the Heterogeneity of Cargo Distribution in the Exogenous Association of Proteins With Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
We characterized the distribution of cargo proteins associated with extracellular vesicles using various exogenous loading methods. In all cases, single‐particle analysis revealed that the distribution of protein content per EV is heterogeneous, following an exponential decay function.
Karl Normak, Marcell Papp, Carolina Paganini, Andrea Zendrini, Paolo Bergese, Dorothea Pinotsi, Paolo Arosio   +6 more
wiley   +1 more source

Highly ordered clustering of TNFα and BAFF ligand-receptor-intracellular adaptor complexes on a lipid membrane. [PDF]

Nat Commun
Lim CS, Lee J, Kim JW, Lee JO.
europepmc   +1 more source

Dry Martini, a coarse-grained force field for lipid membrane simulations with implicit solvent.

Journal of Chemical Theory and Computation, 2015
C. Arnarez, J. Uusitalo, M. F. Masman, H. Ingólfsson, D. H. de Jong, M. Melo, X. Periole, A. H. de Vries, S. Marrink   +8 more
semanticscholar   +1 more source

Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells

Advanced Healthcare Materials, EarlyView.
Membrane vesicles derived from the probiotic Lacticaseibacillus casei BL23 demonstrate antimicrobial properties against Escherichia coli and a potential biological effect in improving the overall survival of C. elegans infected with Pseudomonas aeruginosa. These vesicles stimulated immune responses in primary cells without causing toxicity. Our results
Cecilia L. D'Antoni, Leila Pourtalebi Jahromi, Lorenzo Sana, Ana Paula Domínguez Rubio, Maja Dorfner, Jennifer Munkert, Heike Danzer, Philipp Arnold, Mikhail Lebedev, Esther Zanin, Oscar E. Pérez, Gregor Fuhrmann   +11 more
wiley   +1 more source

Changes of the lipid membrane structures caused by chain-length-dependent doxorubicin embedment in PEGylated liposomes. [PDF]

J Appl Crystallogr
Kang JJ, Huang ZC, Tang LW, Su CJ, Gao HD, Lee HM, Jeng US.   +6 more
europepmc   +1 more source

Ultrasound‐Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units

Advanced Healthcare Materials, EarlyView.
This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans, Anna P. Constantinou, Matthew J. Kibble, Valeria Nele, Daniel Reumann, Luca Bau, Sebastien J. P. Callens, James P. K. Armstrong, Nicolas Newell, Constantin C. Coussios, Molly M. Stevens, Michael D. Gray   +11 more
wiley   +1 more source

Lipid Membrane Domains Control Actin Network Viscoelasticity. [PDF]

Langmuir
Arnold DP, Takatori SC.
europepmc   +1 more source