Results 141 to 150 of about 3,232,425 (402)

Deletion of Macrophage Vitamin D Receptor Promotes Insulin Resistance and Monocyte Cholesterol Transport to Accelerate Atherosclerosis in Mice

Cell Reports, 2015
Intense effort has been devoted to understanding predisposition to chronic systemic inflammation because it contributes to cardiometabolic disease. We demonstrate that deletion of the macrophage vitamin D receptor (VDR) in mice (KODMAC) is sufficient to ...
Jisu Oh, Amy E. Riek, Isra Darwech, Katsuhiko Funai, JianSu Shao, Kathleen Chin, Oscar L. Sierra, Geert Carmeliet, Richard E. Ostlund Jr., Carlos Bernal-Mizrachi   +9 more
doaj   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

L-carnitine and contribution to normal lipid metabolism:evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]

, 2018
Following an application from Lonza Ltd., submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No1924/2006 via the Competent Authority of Germany, the EFSA Panelon Dietetic Products, Nutrition and Allergies (NDA) was
, Bresson, Jean Louis, Burlingame, Barbara, Dean, Tara, Fairweather-Tait, Susan, Heinonen, Marina, Hirsch-Ernst, Karen Ildico, Mangelsdorf, Inge, Martin, Ambroise, McArdle, Harry J., Naska, Androniki, Neuhäuser-Berthold, Monika, Nowicka, Grażyna, Pentieva, Kristina, Sanz, Yolanda, Siani, Alfonso, Sjödin, Anders, Stern, Martin, Strain, Sean (J. J.)., Tomé, Daniel, Turck, Dominique, Van Loveren, Henk, Vinceti, Marco, Willatts, Peter   +23 more
core   +4 more sources

Lipid metabolism

Current Opinion in Lipidology, 1999
Fielding, BA, Frayn, KN
openaire   +11 more sources

Interrelationship of Glucose and Lipid Metabolism [PDF]

, 1959
Walter N. Shaw, Albert I. Winegrad
openalex   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Characterization of key triacylglycerol biosynthesis processes in rhodococci. [PDF]

, 2016
Oleaginous microorganisms have considerable potential for biofuel and commodity chemical production. Under nitrogen-limitation, Rhodococcus jostii RHA1 grown on benzoate, an analog of lignin depolymerization products, accumulated triacylglycerols (TAGs ...
Amara, Sawsan, Diaz-Salazar, Carlos, Eltis, Lindsay D, Liu, Jie, Otani, Hiroshi, Seghezzi, Nicolas   +5 more
core   +2 more sources

Differences in LDL subspecies involve alterations in lipid composition and conformational changes in apolipoprotein B

Journal of Lipid Research, 1996
In order to investigate causes of variability in low density lipoprotein (LDL) particle size, we have assessed LDL composition in plasma from 66 subjects, each with a single LDL band, by 2-16% gradient gel electrophoresis, with a total of eight discrete ...
J R McNamara, D M Small, Z Li, E J Schaefer   +3 more
doaj   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Research progress on gut microbiota-mediated early life influencing factors on childhood obesity

Zhongguo gonggong weisheng
The early stage of life is a critical period for the colonization and formation of the gut microbiota. Research has shown that the colonization and formation of the gut microbiota in the early stage of life is associated with the development of obesity ...
Xiaochuan WANG, Borui LIU, Ningyu WAN, Lu ZHENG, Zhe YANG, Jiajin HU, Deliang WEN   +6 more
doaj   +1 more source