Results 191 to 200 of about 1,222,168 (350)

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

Editorial: The impact of lipid metabolism on cancer progression and metastasis. [PDF]

Front Med (Lausanne)
Aydemir D, Martin-Perez M, Sunami Y.
europepmc   +1 more source

Synthetic Cell‐Based Tissues for Bottom‐Up Assembly of Artificial Lymphatic Organs

Advanced Healthcare Materials, EarlyView.
Synthetic cells have emerged as a novel biomimetic approach for fundamental research and therapeutic interventions. T cell activating synthetic cells are able to form 3D tissue‐like structures by self‐assembly into lymphatic bottom‐up tissues (lymphBUT) with tunable biochemical and biomechanical functionalities as well as metabolic activity are ...
Anna Burgstaller, Tamara Nink, Niklas Walter, Erick Angel Lopez Lopez, Hsin‐Fang Chang, Oskar Staufer   +5 more
wiley   +1 more source

Caveolin-1 regulates lipid droplet metabolism in endothelial cells via autocrine prostacyclin–stimulated, cAMP-mediated lipolysis [PDF]

, 2018
Gross, Richard W., Kuo, Andrew, Lee, Monica Y., Sessa, William C., Yang, Kui   +4 more
core   +2 more sources

Nuclear receptors, transcription factors linking lipid metabolism and immunity: the case of peroxisome proliferator‐activated receptor gamma

, 2008
Tamás Varga, László Nagy
openalex   +2 more sources

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

Critical role of lipid metabolism in axial myopia development. [PDF]

Int J Ophthalmol
Ai LQ, Zhu LY, Yang H, Ye J.
europepmc   +1 more source

Changes in lipid metabolism in pediatric patients with severe sepsis and septic shock

, 2017
Ana Carolina Gouvêa Bermudes, Werther Brunow de Carvalho, Patrícia Zamberlan, Giovana Muramoto, Raul Cavalcante Maranhão, Artur Figueiredo Delgado   +5 more
openalex   +1 more source

Improved Glucose and Lipid Metabolism in Genetically Obese Mice Lacking aP2 [PDF]

, 2000
K. Teoman Uysal, Ludger Scheja, Sarah M. Wiesbrock, Susan Bonner‐Weir, Gökhan S. Hotamışlıgil   +4 more
openalex   +1 more source

Doxorubicin‐Loaded Metal–Organic Framework for Ferroptosis‐Enhanced Chemotherapy Through Sustained Zn Release and Glutathione Peroxidase Downregulation

Advanced Healthcare Materials, EarlyView.
A robust zinc‐based metal–organic framework (ZnMOF) enables dual functions of doxorubicin delivery and sustained Zn2+ release to trigger ferroptosis‐enhnaced chemotherapy. DOX@ZnMOF effectively depletes intracellular glutathione, suppresses GPX4, and elevates reactive oxygen species, leading to efficient oxidative DNA damage and apoptosis.
Xin Ma, Chenghua Deng, Chaoyu Wang, Langston Tilman, Jinhong Li, Wenbin Lin   +5 more
wiley   +1 more source