Results 231 to 240 of about 590,317 (332)
Shrimp Virus Regulates ROS Dynamics via the Nrf2 Pathway to Facilitate Viral Replication
Advanced Science, EarlyView.Viruses manipulate host ROS as a strategy to achieve successful infection. WSSV exploits Nrf2 pathway to maintain ROS homeostasis and establishes a positive feedback loop to facilitate WSSV replication. Wsv220 competitively binds to Keap1 to activate Nrf2. Nrf2 up‐regulates LvG6PDH to produce more NADPH and GSH to eliminate excessive ROS.
Honghui He +6 more
wiley +1 more source
Laboratory yeast strains are highly diverse in lipid metabolism
Renne MF +5 more
europepmc +1 more source
Lipid metabolism in multiple myeloma: pathogenesis, therapeutic opportunities, and future directions. [PDF]
Front OncolWang H +7 more
europepmc +1 more source
Advanced Science, EarlyView.An embedded bioprinting enabled‐arrayed patient‐derived organoids (Eba‐PDO) platform that replicates intrinsic and extrinsic tumor characteristics is introduced. Eba‐PDOs more accurately mimic tissue than standard PDOs (Std‐PDOs) due to maturation in the tumor microenvironment.
Jonghyeuk Han +15 more
wiley +1 more source
AKT1 Phosphorylates FDX1 to Promote Cuproptosis Resistance in Triple‐Negative Breast Cancer
Advanced Science, EarlyView.This study demonstrates that copper activates the AKT signaling pathway, which inhibits ferredoxin‐1 (FDX1), a key regulator of cuproptosis. AKT1‐mediated FDX1 phosphorylation not only abrogates FDX1‐induced cuproptosis and aerobic respiration but also promotes glycolysis.
Zicheng Sun +10 more
wiley +1 more source
Effects of Aging on Glucose and Lipid Metabolism in Mice. [PDF]
Aging CellLien EC +8 more
europepmc +1 more source