Results 171 to 180 of about 133,206 (305)

Nb2C‐Reinforced Hydrogel Microneedle as Dual ROS‐Scavenging Platform to Promote Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
An advanced microneedle patch integrating niobium carbide nanosheets and curcumin is engineered for diabetic wound healing. The system enables dual ROS scavenging and NIR‐enhanced antimicrobial activity, effectively rebalancing the oxidative microenvironment, promoting macrophage repolarization and angiogenesis, and accelerating full‐thickness wound ...
Zhi Zheng, Heyan Huang, Xiangru Chen, Jie Fu, Zhiwei Sun, Mengjuan Tao, Jianwei Mao, Fei Zhang, Zhou Wan, Yuan Li, Dingan Wu, Chuchao Zhou, Yanqing Yang   +12 more
wiley   +1 more source

High-Throughput Strategies for Streamlining Lipid Nanoparticle Development Pipeline. [PDF]

Adv Sci (Weinh)
Lam L, Watson S, Ramaswamy Y, Singh G.
europepmc   +1 more source

Ultrasound‐Triggered Nanobubbles for Endothelial‐Targeted Drug Delivery in the Detection and Treatment of Doxorubicin‐Induced Cardiotoxicity

Advanced Healthcare Materials, EarlyView.
The DA/VTP‐NBs selectively recognized cardiac ECs damaged by DIC and achieved cell‐level targeted imaging. Then US‐triggered controlled release successfully enabled the release of DAPA within the DA/VTP‐NBs at the site of injury. This precise on‐demand drug release approach amplifies a series of localized therapeutic effects through the mtDNA‐mediated ...
Jun Zhang, Yi Ling, Xin Li, Deng Liu, Li Dong, Xuemei Chen, Yingxin Sun, Yongning Shang, Yanli Guo   +8 more
wiley   +1 more source

PEGylated lipids in lipid nanoparticle delivery dynamics and therapeutic innovation. [PDF]

Beilstein J Nanotechnol
Gao P.
europepmc   +1 more source

Biofilm‐Antagonist Ginger‐Based 3D‐Printable Photoresins for Complex Implant Designs Exhibiting Advanced Multifunctional Biomedical Applications

Advanced Materials, EarlyView.
This work offers unique Ginger‐based 3D‐printable resins that can print customizable high‐resolution complex designs. The customizable printing backbone of Zingerol prints also mimics various human bones' strength. Acquisition of in‐vivo biocompatibility in rat model with no severe inflammatory response, along with in‐vitro antioxidant and ex‐vivo anti‐
Simran Jindal, Majd Bisharat, Bassma Khamaisi, Krishanu Ghosal, Eid Nassar‐Marjiya, Qi Wu, Shadi Daoud, Idan Redenski, Samer Srouji, Shady Farah   +9 more
wiley   +1 more source

Lipid nanoparticle-mediated Cd14 siRNA delivery ameliorates the acute inflammatory response to intracortical microelectrode implantation. [PDF]

Acta Biomater
Graham F, Hutchinson DW, Moon TJ, Wang J, Flores-Jimenez H, Druschel L, Ogunnaike L, Gao Y, Smith T, DeTillio S, Goelz C, Bhalotia A, Newman L, Hess-Dunning A, Capadona JR, Karathanasis E.   +15 more
europepmc   +1 more source

Intrinsically Disordered Protein‐Inspired Nanovector‐Based Coacervates for the Direct Cytosolic Transport of Biomacromolecules

Advanced Materials, EarlyView.
Intrinsically disordered protein‐inspired nanovectors (IDP‐NVs) form stable nanocoacervates (NCs) with diverse biomacromolecules. In situ conformational changes confer stability and adaptability to NCs under dynamically changing physiological conditions.
Soyeong Jin, Hyemin Park, Seuk‐Min Ryu, Dagyeong Guk, Jaeeun Lee, Seongeon Jin, Changjoon Keum, Jinyoung Park, Myoung‐Hwan Park, Chaekyu Kim, Hojun Kim, Jaegeun Noh, Kwan Hyi Lee, Ja‐Hyoung Ryu, Youngdo Jeong   +14 more
wiley   +1 more source

Lipid Nanoparticle Library Screen Reveals Lymphatic Endothelial Cell-Targeting Lipid Nanoparticle for Delivering Vascular Endothelial Growth Factor C mRNA after Lymphatic Injury. [PDF]

ACS Nano
Michalaki E, Jeong K, Chin R, Qi Z, Liebman L, González-Vargas Y, Echeverri ES, Paunovska K, Muramatsu H, Pardi N, Tamburini BJ, Jakus Z, Dahlman JE, Dixon JB.   +13 more
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

ApoE is Secreted as a Lipid Nanoparticle by Mammalian Cells: Implications for Alzheimer's Disease Pathogenesis. [PDF]

Biochemistry
Hernandez Arriaza R, Reil D, Fatuzzo N, Fu M, Dai Y, Fernandez Martinez D, Jiang H, Holtzman DM, Greicius MD, Khosla C.   +9 more
europepmc   +1 more source