Results 201 to 210 of about 133,206 (305)

The Vegan Villain Sets Out to The End of Summer: Functionalized Coatings as Biohybrid UV‐Sensors

Advanced Materials Interfaces, EarlyView.
This study introduces biohybrid coatings incorporating E. coli biomass expressing photoconvertible fluorescent proteins as UV‐A responsive elements. Upon irradiation at 400 nm, the coatings exhibit an irreversible fluorescence shift from green to red within 15 min. Notably, the photoconversion capability is retained after >1 year of storage.
Amelie Skopp, Matea Marosevic, Broder Rühmann, Volker Sieber   +3 more
wiley   +1 more source

Advances in mRNA-Based Melanoma Vaccines: A Narrative Review of Lipid Nanoparticle and Dendritic Cell Delivery Platforms. [PDF]

Cells
Sisk CK, Turner LM, Meraj S, Yusuf N.
europepmc   +1 more source

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

Advanced Materials Interfaces, EarlyView.
xx xx. ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation ...
Tang Yuqing, Chen Hong, Fan Weijing, Huang Renyan, You Yang, Liu Guobin   +5 more
wiley   +1 more source

Ionizable guanidine-based lipid nanoparticle for targeted mRNA delivery and cancer immunotherapy. [PDF]

Sci Adv
Zhang H, Liu D, Yang K, Liang Z, Li M.
europepmc   +1 more source

Cholesterol‐DNA Origami Nanostructures for Synthetic Lipid Rafts Induce Early T Cell Activation Signals

Advanced Materials Interfaces, EarlyView.
Here, we present a nanotechnology approach to construct synthetic lipid rafts on the live T cell membrane, leveraging a versatile DNA origami‐enabled platform named as the “cholesterol nano‐patch” (CNP). Our investigation highlights the effectiveness of DNA nanotechnology in exploring the impact of nanoscale arrangement of cholesterols on the ...
Yunmin Jung, Young‐Joo Kim, Kunwoo Noh, Sunmi Lee, Minsuk Kwak   +4 more
wiley   +1 more source

Lipid nanoparticle formulation for gene editing and RNA-based therapies for glioblastoma. [PDF]

Neuro Oncol
Zhang Y, Rabinovsky R, Deforzh E, Kobayashi A, Kuzkina A, Varghese JF, Rai D, Korecka JA, Khurana V, Murugaiyan G, Morrissey D, Uhlmann EJ, Krichevsky AM.   +12 more
europepmc   +1 more source

Radiotherapy Enhancement by Gold Nanocluster‐functionalized Nanoliposomes Using Polychromatic Orthovoltage X‐ray Irradiation

Advanced Materials Interfaces, EarlyView.
Lipid drug carriers to which ultra‐small gold nanoparticles were added enabled more efficient radiotherapy of cultured pancreatic cancer tumors. These nanoparticles boosted radiation‐induced damage to tumors by generating more reactive molecules, though higher gold levels are needed for strong benefits.
Nazareth Milagros Carigga Gutierrez, Eaazhisai Kandiah, Sofia Leo, Erwan Dupont, Fabrizio Johnson‐Corrales, Marc‐André Hograindleur, Sarvenaz Keshmiri, Hélène Elleaume, Benoit Busser, Romain Haudecoeur, Véronique Jacob, Anthony Vella, Véronique Josserand, Maxime Henry, Jean‐Luc Coll, Amandine Hurbin, Xavier Le Guével, Mans Broekgaarden   +17 more
wiley   +1 more source

Structure-Activity Relationship of Ionizable Lipids for siRNA and mRNA Lipid Nanoparticle Design. [PDF]

ACS Biomater Sci Eng
Lee SM, Sun Y, Chatterjee S, Xiong H, Cheng Q, Wang X, Siegwart DJ.   +6 more
europepmc   +1 more source

A High Throughput Microfluidic Approach for the Continuous Manufacture of Ibuprofen Nanocrystals

Advanced Materials Technologies, EarlyView.
A robust, continuous manufacturing platform using a high‐throughput microfluidic reactor addresses key scalability challenges in pharmaceutical production. This process efficiently generates crystalline ibuprofen nanoparticles with superior control over size and distribution.
Shorooq Abukhamees, Maximilian Besenhard, Rawan Fitaihi, Hei Ming Kenneth Ho, Asterios Gavriilidis, Duncan Q. M. Craig   +5 more
wiley   +1 more source

Allergen-specific mRNA-lipid nanoparticle therapy for prevention and treatment of experimental allergy in mice. [PDF]

J Clin Invest
Rochman Y, Kotliar M, Klingler AM, Rochman M, Alameh MG, Melamed JR, Osswald GA, Caldwell JM, Felton JM, Mack LE, Hargis J, Lewkowich IP, Barski A, Weissman D, Rothenberg ME.   +14 more
europepmc   +1 more source