Results 201 to 210 of about 117,691 (310)

Targeting macrophages in the tumor-microenvironment to enhance their anti-tumorous functions by gene silencing using optimized siRNA-loaded lipid nanoparticles [an abstract of entire text]

, 2019
Nour Shobaki
openalex   +1 more source

A High Throughput Microfluidic Approach for the Continuous Manufacture of Ibuprofen Nanocrystals

Advanced Materials Technologies, EarlyView.
A robust, continuous manufacturing platform using a high‐throughput microfluidic reactor addresses key scalability challenges in pharmaceutical production. This process efficiently generates crystalline ibuprofen nanoparticles with superior control over size and distribution.
Shorooq Abukhamees, Maximilian Besenhard, Rawan Fitaihi, Hei Ming Kenneth Ho, Asterios Gavriilidis, Duncan Q. M. Craig   +5 more
wiley   +1 more source

pH-Dependent Release and Folate Receptor Alpha (FRα) Targeting To Allow Exclusive Targeting of Lipid-Nanoparticles (LNP)

Meghan A. Cymbron, Densika Ravindiralingam, Thomas Liang   +2 more
openalex   +2 more sources

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

Advances in nanomaterial-mediated CRISPR/Cas delivery: from lipid nanoparticles to vesicle-derived systems. [PDF]

Front Bioeng Biotechnol
Wang B, Lu J, Zhang X, Hu R, Ma H.
europepmc   +1 more source

Microfluidic Hydroporation Platform for Effective Allogeneic CAR‐T Cell Production and Subsequent Functional Cytotoxicity Analysis

Advanced Materials Technologies, EarlyView.
The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon, Sein Kim, Hyun‐Young Kim, Duck Cho, Sungsu Park, Seohyun Kim, Aram J. Chung   +6 more
wiley   +1 more source

Photosensitizing Lipid Nanoparticles for Ferroptosis-Enhanced Photodynamic Cancer Therapy via GPX4 Silencing. [PDF]

Adv Healthc Mater
Bae GH, Shin S, Park JD, Koh EY, Ko S, Han J, Park CG, Kim DH, Na K, Park W.   +9 more
europepmc   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source

Tumor mRNA-lipid nanoparticles via chimeric nanobody-lipid co-assembly. [PDF]

Theranostics
Zhu C, Wang J, Rahman MM, Zhang Y, Wang L, Wan Y.   +5 more
europepmc   +1 more source

In Vivo mRNA CAR T Cell Engineering via Targeted Lipid Nanoparticles 

Therapeutic Innovation Australia
openalex   +1 more source