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Physicochemical Design and <i>In Vitro</i> Evaluation of Diterpene Phytol-Loaded Solid Lipid Nanoparticles. [PDF]
Tavares-Pessoa LCS +6 more
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On-Chip De Novo Production of mRNA Vaccine in Lipid Nanoparticles. [PDF]
Zilberzwige-Tal S +13 more
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Influence of polyethylene glycol on the mucus penetration and stability of lipid nanoparticles in cryopreservation and lyophilization. [PDF]
Wang X +5 more
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Pulmonary delivery of siRNA lipoplexes and lipid nanoparticles using a vibrating mesh nebuliser.
Neary MT +8 more
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Carbohydrate anchored lipid nanoparticles
International Journal of Pharmaceutics, 2022Nanotechnology has been a dynamic field for formulation scientists with multidisciplinary research being conducted worldwide. Advancements in development of functional nanosystems have led to evolution of breakthrough technologies. Lipidic nanosystems, in particular, are highly preferred owing to their non-immunogenic safety profiles along with a range
Pratik, Kakade +4 more
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Lipid Packing in Lipid-Wrapped Nanoparticles
The Journal of Physical Chemistry B, 2018Equilibrium simulations of lipid-wrapped nanoparticles (LNP) were performed using a hybrid molecular dynamics/Monte Carlo (MD/MC) approach. The radius, R, of a spherical nanoparticle (NP) core was adjusted with MC moves while a surrounding lipid bilayer was treated with MD.
David Stelter, Tom Keyes
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2020
Recent advances in the development of nanocarriers have started a new era in Formulation Science. Among various nanoparticles, solid lipid nanoparticles (SLNs) offer an attractive carrier system to conventional colloidal carriers, such as emulsions, microemulsions, self micro-emulsifying drug delivery system, micellar systems, liposomes, polymeric ...
Akhlesh Kumar Jain, Suresh Thareja
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Recent advances in the development of nanocarriers have started a new era in Formulation Science. Among various nanoparticles, solid lipid nanoparticles (SLNs) offer an attractive carrier system to conventional colloidal carriers, such as emulsions, microemulsions, self micro-emulsifying drug delivery system, micellar systems, liposomes, polymeric ...
Akhlesh Kumar Jain, Suresh Thareja
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2021
The present invention relates to the field of lipid nanoparticles (LNP); more specifically comprising an ionizable lipid, a phospholipid, a sterol, a PEG lipid and one or more nucleic acids. The LNP's of the present invention are characterized in comprising less than about 1 mol% of a C18-PEG2000 lipid.
Bevers, Sanne +3 more
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The present invention relates to the field of lipid nanoparticles (LNP); more specifically comprising an ionizable lipid, a phospholipid, a sterol, a PEG lipid and one or more nucleic acids. The LNP's of the present invention are characterized in comprising less than about 1 mol% of a C18-PEG2000 lipid.
Bevers, Sanne +3 more
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2023
The present invention relates to the field of lipid nanoparticles (LPN); more specifically comprising an ionisable lipid, a phospholipid, a sterol, a PEG lipid and one or more nucleic acids. The LNP's of the present invention are characterized in having a minimal average diameter of about 140 nm, thereby inducing a more potent immune response.
De Koker, Stefaan +2 more
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The present invention relates to the field of lipid nanoparticles (LPN); more specifically comprising an ionisable lipid, a phospholipid, a sterol, a PEG lipid and one or more nucleic acids. The LNP's of the present invention are characterized in having a minimal average diameter of about 140 nm, thereby inducing a more potent immune response.
De Koker, Stefaan +2 more
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Stability of Lipid Excipients in Solid Lipid Nanoparticles
ChemInform, 2007AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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