Results 231 to 240 of about 12,002 (336)

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, Volume 13, Issue 10, 18 February 2026.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

Combining Anti-Inflammatory Drugs and Cell-Specific Expression-Suppression Reduces the Adjuvant Activity of mRNA-LNPs. [PDF]

Mol Pharm
Tanaka H, Nishiumi N, Shirane D, Kosegawa Y, Siril YJ, Akita H.   +5 more
europepmc   +1 more source

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, Volume 13, Issue 10, 18 February 2026.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

Aminoglycoside Drugs as Adjuvants to Enhance siRNA/mRNA Delivery by Lipid Nanoparticles. [PDF]

ACS Omega
Sun X, Qian L.
europepmc   +1 more source

Antibody‐Empowered Nanomedicine for Precise Biomedical Applications

Advanced Science, Volume 13, Issue 10, 18 February 2026.
This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen, Xinglin Chen, Zhenhao Gao, Meng Sun, Yaozong Yu, Fang Lv, Qiujun Wang, Jinfeng Zhang   +7 more
wiley   +1 more source

Effects of Serum Incubation on Lipid Nanoparticle PEG Shedding, mRNA Retention, and Membrane Interactions. [PDF]

ACS Appl Mater Interfaces
Niederkofler S, Parkkila P, Aliakbarinodehi N, Sasanian N, Emilsson G, Ulkoski D, Ferreira CJO, Galenkamp NS, Silva BFB, Lundberg D, Jing Y, Lindfors L, Agnarsson B, Höök F.   +13 more
europepmc   +1 more source

Pickering or Non‐Pickering Dilemma: A Complicated System of Anionic Lignin‐Incorporated Oil‐Water Emulsions

ChemSusChem, Volume 19, Issue 3, February 2026.
Sulfoethylated and carboxyethylated lignin derivatives were fabricated, and their impacts on stabilizing soybean oil–water were analyzed in Pickering and non‐Pickering systems. It was noticed that the lignin derivatives behaved very differently, implying that the modification routes played an important role in their performance.
Saba Khodavandegar, Ulrica Edlund, Peter Rättö, Illia Dobryden, Pedram Fatehi   +4 more
wiley   +1 more source

Recent advances in lipid nanoparticles for cancer vaccine delivery: Challenges and future perspectives. [PDF]

Int J Pharm X
Hasan N, Aftab M, Ikram S, Mustofa AZ, Sriwidodo S, Darusman HS, Amir MN, Tockary TA, Uchida S.   +8 more
europepmc   +1 more source

Amoxicillin-loaded lipid nanoparticles against Helicobacter pylori infections [PDF]

, 2016
Ana Rita Oliveira Macedo Pinto
core  

Encapsulation of Dexamethasone into mRNA–Lipid Nanoparticles Is a Promising Approach for the Development of Liver-Targeted Anti-Inflammatory Therapies [PDF]

Cacicedo, M., Fraude-El Ghazi, S., Gambaro, R., Gehring, S., Huck-Iriart, C., Islan, G., Landfester, K., Lieberwirth, I., Limeres, M., Pretsch, L., Rivero Berti, I., Si, S., Svensson, M.   +12 more
core   +2 more sources